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Switching from Wegovy to Mounjaro: How To Guide for Patients

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, 6 min read

Switching from Wegovy to Mounjaro: How To Guide for Patients

Are you on a weight management journey but feel like you've hit a plateau with your current medication? You may have wondered if there's another option that might align better with your health goals, lifestyle, and preferences. For those navigating the complexities of weight loss, the decision to switch from Wegovy to Mounjaro could open up new possibilities for achieving your desired outcomes. Mounjaro has been noted for its significant impact on weight loss in clinical trials, with some individuals experiencing around 25% weight loss over a year. 

With considerations ranging from personal experiences with side effects to the quest for more effective results, and even the practicalities of medication availability, making an informed switch might be the next step in your health and wellness journey. 

If you are thinking about  transitioning from Wegovy to Mounjaro, this guide explores who is eligible for such a change, and outlines the thoughtful approach required to ensure a smooth and successful switch. Let's embark on this exploration together, with the hope of unlocking a path that leads you closer to your weight management goals.

Can You Switch from Wegovy to Mounjaro?

Yes, you can switch from Wegovy to Mounjaro for weight management, but it's vital to do so under the guidance of a healthcare professional. The two medications should not be used simultaneously. Your doctor will help determine if Mounjaro is a suitable option for you and advise on a safe transition, including any necessary "washout" periods between medications. Factors like side effects, weight loss effectiveness, and your individual health profile will be considered in their recommendation.

An infographic comparing Wegovy and Mounjaro, highlighting similarities, differences, and considerations for switching

Why Consider the Switch?

  • Patient Preference: Personal choice plays a significant role in managing one's health. Patients might prefer one medication over another based on their experiences, lifestyle compatibility, or simply because they believe one option may work better for them.
  • Side Effects: While both medications have similar side effect profiles, individuals may respond differently to each. If you're experiencing side effects with Wegovy, switching to Mounjaro might result in a better experience, although it's important to note that individual reactions can vary.
  • Superior Effect in Some Patients: Clinical studies have indicated that Mounjaro can lead to a greater average weight loss in some patients compared to Wegovy. Those who haven't achieved their desired results with Wegovy might find Mounjaro to be a more effective option.
  • Availability: Currently, Mounjaro generally has better availability in the UK, which might make it a more convenient option for some patients. However, it's worth noting that the availability of Wegovy is also improving.
  • Cost Implications: In the context of a Wegovy shortage, prices for the medication have trended higher when sought privately. On the other hand, Mounjaro's better availability may offer a more cost-effective alternative for those considering the switch. It's important to research and compare the current private market prices of both medications. Opting for Mounjaro could potentially offer financial relief without compromising the effectiveness of your weight management plan.

Who is Eligible to Switch?

Eligibility for switching from Wegovy to Mounjaro largely aligns with the initial criteria set for Mounjaro use. This includes:

  • Meeting the Body Mass Index (BMI) criteria for Mounjaro treatment.
  • Having no contraindications for taking Mounjaro It is worth noting that the exclusions for both medications are very similar, meaning  that if you were eligible for Wegovy, you are likely to be eligible for Mounjaro too.

Mounjaro vs. Wegovy Comparison in Brief


WegovyMounjaro
Company NameNovo NordiskEli Lilly
Active IngredientSemaglutideTirzepatide
Mechanism of ActionMimics the action of GLP-1, a hormone that helps regulate appetite.Mimics the action of GLP-1 and GIP, hormones that help regulate appetite and blood sugar levels.
Conditions TreatedApproved by MHRA for weight loss in adults with obesity or overweight individuals with weight-related health conditions.  Approved by MHRA for weight loss in adults with obesity or overweight individuals with weight-related health conditions.  
Who Can Take ItBody Mass Index (BMI) of 30 or more; BMI between 27-30 and have weight-related health problems.Body Mass Index (BMI) of 30 or more; BMI between 27-30 and have weight-related health problems.

Before any switch is made, it is very important that a personalised clinical review is conducted to ensure that Mounjaro is a suitable option for you.

How to Switch from Wegovy to Mounjaro?

Switching from one medication to another, especially in the context of weight management, needs to be approached with care. Here’s a general outline of the process:

  1. Stop Taking Wegovy: Your healthcare provider will advise you to stop taking Wegovy as the first step towards making the switch.
  2. Wash Out Period: After stopping Wegovy, there's usually a short "wash out" period, typically a few weeks, but this can vary based on individual circumstances. This period allows Wegovy to leave your system before starting Mounjaro.
  3. Start Mounjaro: Begin with the initiation dose of Mounjaro and gradually increase to the maintenance dose over the following months as advised by your healthcare provider.
  4. Maintenance Dose: Once you reach the maintenance dose, you will continue with this dosage moving forward.

Switching medications is a decision that should not be taken lightly. It requires thoughtful consideration and guidance from healthcare professionals who understand your health journey. It's also important to communicate openly with your healthcare team about your experiences, concerns, and goals throughout this process. Remember, the primary aim is to find the most effective and suitable treatment option for your weight management journey, ensuring it aligns with your overall health objectives and lifestyle.

At the heart of this discussion is the recognition that every patient's journey is unique. We acknowledge the courage it takes to seek help and make changes towards a healthier life. Whether you're considering switching from Wegovy to Mounjaro or exploring other options, know that your efforts are commendable and supported.

Read more: Ozempic vs. Mounjaro: Side Effects, Costs, and Effectiveness

Who Should Not Take Mounjaro

  • Type 1 Diabetes Patients: Mounjaro is not approved for use in individuals with type 1 diabetes. This distinction is crucial as the medication may not be suitable or safe for this particular group of patients.
  • Pancreatitis: People who currently have pancreatitis or have had this condition in the past should avoid Mounjaro treatment. Pancreatitis is a condition characterized by inflammation of the pancreas, and taking Mounjaro in such cases could potentially exacerbate the condition or lead to adverse effects.

    If you want to read information about the risks and contraindications associated with Mounjaro, then you can find more details on this page: Mounjaro Side Effects: What You Need to Know

Switch to eMed Weight Management Programme

If you're considering the switch from Wegovy to Mounjaro, our eMed Weight Management Programme could be the perfect support system for you. As part of our service, we offer more than just medication; we provide a holistic approach to weight management. This includes personalised support from healthcare professionals, tailored advice on diet and exercise, and ongoing encouragement to help you reach your health goals. Our programme is designed to support you every step of the way, ensuring a seamless transition and a successful weight management journey. To learn more about how our service can assist you, please visit our website at eMed Weight Management.


The information provided is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of a doctor with any questions you may have regarding a medical condition. Never delay seeking or disregard professional medical advice because of something you have read here.

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