Application Details | Babylon Health

Babylon US Application Details

App Overview

Version Number: C1R5A1 COREv1.2.0 (iOS), C1R5A1 COREv1.1.2 (Android)

Release: 2019-09-27

Features: Digital health AI services only; no virtual clinical services

Terms of Use

Privacy Policy

Contact: Babylon Health, 801 Barton Springs Rd, Austin, TX 78704, us-support@babylonhealth.com


About Chatbot

Babylon’s Chatbot is a software application that can carry out a conversation with you about symptoms and medical issues. Taking into account your self-reported age and gender, it provides relevant information based on how closely conditions match your answers to questions about symptoms and risk factors.

THE INFORMATION PROVIDED BY THE BABYLON CHATBOT IS INTENDED FOR INFORMATIONAL PURPOSES ONLY. IT IS NOT INTENDED TO BE USED AS MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT RECOMMENDATIONS, OR A SUBSTITUTE FOR A MEDICAL PROFESSIONAL.

You should never take or stop taking any action (such as taking medication) based on information provided by the Chatbot.

The Chatbot will provide different types of information to you based on, among other things, the symptoms entered. One possible output of the symptom checker is the next steps someone experiencing the symptoms entered would usually take. Where the information returned suggests the need for further medical advice, or if you have further questions or concerns, you should always consult with a medical provider. The other possible output is general medical information on the types of conditions that people who have experienced similar symptoms have had, listed in the order (highest to lowest) of how closely the conditions match the symptoms entered, based on symptom prevalence for conditions which are taken from publicly available medical resources.

Information provided about possible medical conditions at the conclusion of the Chatbot conversation is based on a scoring system that ranks conditions from a range of zero (almost impossible match) to 100% (very likely match). The Chatbot will generally provide information about the closest three or four matches based on its mathematical calculations. You can then use the Babylon app to explore more in-depth information about the conditions or speak to a medical provider if you have any questions or concerns. The order in which conditions are listed does not in any way indicate the likelihood of you having or not having a condition.

Babylon’s software is built on various Artificial Intelligence (AI) disciplines including natural language processing, machine learning, and a probabilistic graphical model. The Chatbot relies on various inputs to try to provide information about possible medical conditions. These include personal data from you (the user), expert physician guidance, public health databases, medical research, epidemiology literature, and other verified sources. By way of example, information about conditions is sourced from databases such as PubMed/Medline, which aggregates more than 29 million medical articles from journals, articles and books. The probabilistic graphical model, which guides the interaction between the Chatbot and the user, relies on the combination of both data and expert clinical opinions to influence information provided about possible medical conditions. A full list of references is available below.

Please note that the Chatbot is still learning. At this time, it cannot provide information related to pregnancy or infants.

Chatbot is only intended for individuals aged 18 and over.

About Healthcheck

Healthcheck enables you to understand how your health and wellness may be affected by lifestyle choices, empowering you to achieve your health and wellness goals. It uses extensive epidemiological research to quantify general disease risk factors, and compares these population risk factors to the information entered. The information provided is for informational purposes and consideration of lifestyle changes only.

HEALTHCHECK IS NOT INTENDED TO BE USED OR RELIED ON AS MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT RECOMMENDATIONS, OR SERVE AS A SUBSTITUTE FOR A MEDICAL PROFESSIONAL.

Healthcheck’s questionnaires – which can be completed separately or all at once – include questions about your body, your activity, your nutrition, and your mood. Based on your answers to these questions, Healthcheck builds your condition risk profile, accounting for how each risk component in the questionnaires (e.g., alcohol intake, smoking) could increase or decrease certain disease risks based on the presence of various relevant factors (e.g., family history, lifestyle factors). The comparative risk levels provided are estimated based on your self-reported risk factors as compared to the population. However, your results are not personalized, because there are other factors that may contribute to individual risk. If someone else enters the same answers as you, they will receive the same information, which does not account for unknown factors.

The comparative risk level information Healthcheck provides is a comparison of your statistical risk profile to the average statistical risk for individuals of the same age and gender. The average statistical risk provided is the chance that a given disease might, in purely statistical terms, develop over the next 5 years in a given population. For example, a risk of “3 in 1000” means that if 1000 people provided identical responses to questions related to a heart condition, 3 of them are statistically likely to develop that condition over the next 5 years. A comparative risk that is higher than average does not necessarily suggest a “high” risk, but rather that the information provided suggests a higher statistical risk than other people of the same age and gender. For example, while family history of a disease and increased age are each likely to result in an increased absolute risk level, the increased age alone will not result in a higher comparative risk level. Please note that certain comparative risk level estimates may be more accurate than others. Circumstances which may result in a less accurate comparative risk level may include, but are not limited to: the presence of long-term medical conditions or disabilities; risk factors of which you are unaware or not asked about; the provision of inaccurate information; a large combination of active risk factors; low disease occurrence; and variable lifestyle and risk factors over time.

Information about each comparative disease risk is paired with information about healthy lifestyle changes and commonly known ways to help reduce the risk (e.g., reducing alcohol intake, quitting smoking). The information provided is intended to promote general health and well-being. However, you should only make changes to your lifestyle after having discussed such changes with a medical professional. And you should always discuss any questions or concerns about your health with your doctor.

Information about conditions, symptoms, and epidemiology have been compiled from medical resources such as the National Institute of Health and Care Excellence (NICE), Clinical Knowledge Summaries database, NHS Choices, and by Babylon’s clinicians. A full list of references is available below.

Healthcheck is only suitable for use by adults 18 years of age and over who are not pregnant.

Warnings

  • Do not use the Chatbot in an emergency. In an emergency, please call 911.
  • Chatbot is powered by artificial intelligence and is not a real clinician.
  • Output from Chatbot does not constitute medical advice, diagnosis or treatment; it provides non-personalized information based on the combination of symptoms that a user enters.
  • If your symptoms persist, change or worsen, or you have other questions or concerns about your symptoms, seek further advice from a medical professional.
  • The App is only intended for individuals aged 18 and over. This applies to both Chatbot and Healthcheck.
  • Use of the App is subject to our Terms of Use. Please read these carefully for more information.
  • Chatbot is not suitable if you are experiencing or are at all concerned about any of the following symptoms:
    • Chest pain
    • Severe bleeding
    • Severe difficulty in breathing (shortness of breath)
    • Sudden, severe pain anywhere in the body
    • Moderate to severe burns
    • Convulsions or seizures
    • Sudden change in mental status (such as unusual behavior, confusion, difficulty waking from sleep)
    • Head or spinal injuries
    • Wound or injury caused by an object piercing the skin
    • Serious limb impairment or broken bone
    • Potential signs of severe allergy such as lip or tongue swelling
  • You should always speak to a doctor if you have any questions or concerns about your health. Doing so is especially important if any of the following circumstances apply:
    • Mental health concerns
    • Skin problems
    • Pregnancy and post-natal concerns
    • Recent surgery
    • If your immune system is significantly weak (i.e., due to taking specific medications or an underlying condition)
    • Known HIV or AIDS
    • Active Tuberculosis
    • Fever after travel outside of Europe or North America
    • New or rapidly changing rashes
    • If you are considering harming yourself or taking your own life

Sources and Citations

Chatbot

Chatbot’s proprietary informational content is derived from the medical expertise of Babylon clinicians trained in the practice of evidence-based medicine and clinical guidelines from government and recognized medical societies. All content is medically reviewed by board certified, licensed physicians for medical accuracy and relevancy. Such clinical guidelines and other evidence-based best practices can be found in the following sources:

  • GP notebook – www.gpnotebook.co.uk
  • National Institute for Health and Care Excellence (NICE) guidelines - https://www.nice.org.uk/guidance
  • NHS choices - https://www.nhs.uk/
  • Scottish Intercollegiate Guideline Network (SIGN) guidelines https://www.sign.ac.uk/
  • Adamec, I., Skorić, M.K., Handžić, J. and Habek, M., 2015. Incidence, seasonality and comorbidity in vestibular neuritis. Neurological Sciences, 36(1), pp.91-95.
  • Adams, R.J., Appleton, S.L., Gill, T.K., Taylor, A.W., Wilson, D.H. and Hill, C.L., 2011. Cause for concern in the use of non-steroidal anti-inflammatory medications in the community- a population-based study. BMC Family Practice, 12(1), p.70.
  • Albu, C., Brusin, S., Gomez, J., Ciancio, B. and Spiteri, G., 2014. Sexually transmitted infections, including HIV and blood-borne viruses. Annual Epidemiological Report. ECDC.
  • Amar, R.K., Jick, S.S., Rosenberg, D., Maher, T.M. and Meier, C.R., 2012. Incidence of the pneumoconioses in the United Kingdom general population between 1997 and 2008. Respiration, 84(3), pp.200-206.
  • Anandan, C., Gupta, R., Simpson, C.R., Fischbacher, C. and Sheikh, A., 2009. Epidemiology and disease burden from allergic disease in Scotland: Analyses of national databases. Journal of the Royal Society of Medicine, 102(10), pp.431-442.
  • Attili, A.F., Carulli, N., Roda, E., Barbara, B., Capocaccia, L., Menotti, A., Okoliksanyi, L., Ricci, G., Capocaccia, R., Festi, D. and Lalloni, L., 1995. Epidemiology of gallstone disease in Italy: Prevalence data of the Multicenter Italian Study on Cholelithiasis (M.I.COL.). American Journal of Epidemiology, 141(2), pp.158-165.
  • Bartholomeeusen, S., Vandenbroucke, J., Truyers, C. and Buntinx, F., 2007. Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003. Br J Gen Pract, 57(539), pp.497-499.
  • Bates, B., Cox, L., Nicholson, S., Page, P., Prentice, A., Steer, T. and Swan, G., 2016. National Diet and Nutrition Survey results from years 5 and 6 (combined) of the Rolling Programme (2012/2013–2013/2014). Public Health England: London, UK.
  • Becker, C., Brobert, G.P., Almqvist, P.M., Johansson, S., Jick, S.S. and Meier, C.R., 2008. Migraine incidence, comorbidity and health resource utilization in the UK. Cephalalgia, 28(1), pp.57-64.
  • Benson, V. and Marano, M.A., 1998. Current estimates from the National Health Interview Survey, 1995. National Center for Health Statistics. Vital Health Stat 10(199).
  • Bharucha, A.E., Parthasarathy, G., Ditah, I., Fletcher, J.G., Ewelukwa, O., Pendlimari, R., Yawn, B.P., Melton, L.J., Schleck, C. and Zinsmeister, A.R., 2015. Temporal trends in the incidence and natural history of diverticulitis: A population-based study. The American Journal of Gastroenterology, 110(11), p.1589.
  • Birtwhistle, R., Morkem, R., Peat, G., Williamson, T., Green, M.E., Khan, S. and Jordan, K.P., 2015. Prevalence and management of osteoarthritis in primary care: An epidemiologic cohort study from the Canadian Primary Care Sentinel Surveillance Network. CMAJ Open, 3(3), p.E270.
  • Blanco, C., Okuda, M., Markowitz, J.C., Liu, S.M., Grant, B.F. and Hasin, D.S., 2010. The epidemiology of chronic major depressive disorder and dysthymic disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. The Journal of Clinical Psychiatry, 71(12), p.1645.
  • Bleeker, M.C., Visser, P.J., Overbeek, L.I., van Beurden, M. and Berkhof, J., 2016. Lichen sclerosus: Incidence and risk of vulvar squamous cell carcinoma. Cancer Epidemiology and Prevention Biomarkers, 25(8), pp.1224-1230.
  • Boonstra, K., Kunst, A.E., Stadhouders, P.H., Tuynman, H.A., Poen, A.C., van Nieuwkerk, K.M., Witteman, E.M., Hamann, D., Witteman, B.J., Beuers, U. and Ponsioen, C.Y., 2014. Rising incidence and prevalence of primary biliary cirrhosis: A large population‐based study. Liver International, 34(6), pp.e31-e38.
  • Bot, S.D., Van der Waal, J.M., Terwee, C.B., Van der Windt, D.A.W.M., Schellevis, F.G., Bouter, L.M. and Dekker, J., 2005. Incidence and prevalence of complaints of the neck and upper extremity in general practice. Annals of the Rheumatic Diseases, 64(1), pp.118-123.
  • British Lung Foundation, 2018. Asthma statistics [online]. British Lung Foundation. [viewed 23 February 2018]. Available from: https://statistics.blf.org.uk/asthma
  • British Lung Foundation, 2018. Bronchiectasis statistics [online]. British Lung Foundation. [viewed 1 June 2018]. Available from: https://statistics.blf.org.uk/bronchiectasis
  • British Lung Foundation, 2018. Pneumonia statistics [online]. Lung Foundation. [viewed 26 July 2018]. Available from: https://statistics.blf.org.uk/pneumonia
  • Brown, L. and Neave, A., 2016. Health Survey for England 2015: Adult alcohol consumption. Leeds, UK: Health and Social Care Information Centre.
  • Browning, G.G. and Gatehouse, S., 1992. The prevalence of middle ear disease in the adult British population. Clinical Otolaryngology & Allied Sciences, 17(4), pp.317-321.
  • Bruderer, S.G., Bodmer, D., Stohler, N.A., Jick, S.S. and Meier, C.R., 2017. Population-based study on the epidemiology of Ménière's disease. Audiology and Neurotology, 22(2), pp.74-82.
  • Cancer Research UK, 2018. Acute myeloid leukaemia (AML) incidence statistics [online]. Cancer Research UK. [viewed 17 April 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/leukaemia-aml/incidence
  • Cancer Research UK, 2018. Anal cancer incidence statistics [online]. Cancer Research UK. [viewed 22 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/anal-cancer/incidence
  • Cancer Research UK, 2018. Bladder cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bladder-cancer/incidence
  • Cancer Research UK, 2018. Bone sarcoma incidence statistics [online]. Cancer Research UK. [viewed 4 May 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bone-sarcoma/incidence
  • Cancer Research UK, 2018. Bowel cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bowel-cancer/incidence
  • Cancer Research UK, 2018. Breast cancer incidence (invasive) statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer/incidence-invasive
  • Cancer Research UK, 2018. Cervical cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/cervical-cancer/incidence
  • Cancer Research UK, 2018. Chronic lymphocytic leukaemia (CLL) incidence statistics [online]. Cancer Research UK. [viewed 17 April 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/leukaemia-cll/incidence
  • Cancer Research UK, 2018. Gallbladder cancer incidence statistics [online]. Cancer Research UK. [viewed 19 March 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/gallbladder-cancer/incidence
  • Cancer Research UK, 2018. Hodgkin lymphoma incidence statistics [online]. Cancer Research UK. [viewed 16 April 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/hodgkin-lymphoma/incidence
  • Cancer Research UK, 2018. Kidney cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/kidney-cancer/incidence
  • Cancer Research UK, 2018. Liver cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/liver-cancer/incidence
  • Cancer Research UK, 2018. Lung cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/lung-cancer/incidence
  • Cancer Research UK, 2018. Mesothelioma incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/mesothelioma/incidence
  • Cancer Research UK, 2018. Myeloma incidence statistics [online]. Cancer Research UK. [viewed 4 May 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/myeloma/incidence
  • Cancer Research UK, 2018. Non-Hodgkin lymphoma incidence statistics [online]. Cancer Research UK. [viewed 19 March 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/non-hodgkin-lymphoma/incidence
  • Cancer Research UK, 2018. Oesophageal cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/oesophageal-cancer/incidence
  • Cancer Research UK, 2018. Ovarian cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/ovarian-cancer/incidence
  • Cancer Research UK, 2018. Pancreatic cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/pancreatic-cancer/incidence
  • Cancer Research UK, 2018. Penile cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/penile-cancer/incidence
  • Cancer Research UK, 2018. Prostate cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.o...
  • Cancer Research UK, 2018. Stomach cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/stomach-cancer/incidence
  • Cancer Research UK, 2018. Testicular cancer incidence statistics [online]. Cancer Research UK. [viewed 6 June 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/testicular-cancer/incidence
  • Cancer Research UK, 2018. Uterine cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/uterine-cancer/incidence
  • Cancer Research UK, 2018. Vaginal cancer incidence statistics [online]. Cancer Research UK. [viewed 13 April 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/vaginal-cancer/incidence
  • Cancer Research UK, 2018. Vulval cancer incidence statistics [online]. Cancer Research UK. [viewed 21 February 2018]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/vulval-cancer/incidence
  • Carbone, L.D., Cooper, C., Michet, C.J., Atkinson, E.J., Michael O'Fallon, W. and Joseph Melton, L., 1992. Ankylosing spondylitis in Rochester, Minnesota, 1935–1989. Is the epidemiology changing?. Arthritis & Rheumatism, 35(12), pp.1476-1482.
  • Card, T.R., Solaymani-Dodaran, M. and West, J., 2008. Incidence and mortality of primary sclerosing cholangitis in the UK: A population-based cohort study. Journal of Hepatology, 48(6), pp.939-944.
  • Carpentier, P.H., Maricq, H.R., Biro, C., Ponçot-Makinen, C.O. and Franco, A., 2004. Prevalence, risk factors, and clinical patterns of chronic venous disorders of lower limbs: A population-based study in France. Journal of Vascular Surgery, 40(4), pp.650-659.
  • Cassell, J.A., Mercer, C.H., Sutcliffe, L., Petersen, I., Islam, A., Brook, M.G., Ross, J.D., Kinghorn, G.R., Simms, I., Hughes, G. and Majeed, A., 2006. Trends in sexually transmitted infections in general practice 1990-2000: Population based study using data from the UK General Practice Research Database. BMJ, 332(7537), pp.332-334.
  • Cassidy, A., Myles, J.P., Duffy, S.W., Liloglou, T. and Field, J.K., 2006. Family history and risk of lung cancer: Age-at-diagnosis in cases and first-degree relatives. British Journal of Cancer, 95(9), p.1288.
  • Cea Soriano, L., López-Garcia, E., Schulze-Rath, R. and Garcia Rodríguez, L.A., 2017. Incidence, treatment and recurrence of endometriosis in a UK-based population analysis using data from The Health Improvement Network and the Hospital Episode Statistics database. The European Journal of Contraception & Reproductive Health Care, 22(5), pp.334-343.
  • Cea-Soriano, L., Fowkes, F.G.R., Johansson, S., Allum, A.M. and Rodriguez, L.A.G., 2018. Time trends in peripheral artery disease incidence, prevalence and secondary preventive therapy: A cohort study in The Health Improvement Network in the UK. BMJ Open, 8(1), p.e018184.
  • Centers for Disease Control and Prevention (CDC), 2011. Estimated burden of acute otitis externa--United States, 2003-2007. MMWR: Morbidity and Mortality Weekly Report, 60(19), p.605.
  • Centers for Disease Control and Prevention (CDC), 2012. Prevalence of stroke--United States, 2006-2010. MMWR: Morbidity and Mortality Weekly Report, 61(20), p.379.
  • Cesarone, M.R., Belcaro, G., Nicolaides, A.N., Geroulakos, G., Griffin, M., Incandela, L., De Sanctis, M.T., Sabetai, M., Geroulakos, G., Agus, G. and Bavera, P., 2002. 'Real' epidemiology of varicose veins and chronic venous diseases: The San Valentino Vascular Screening Project. Angiology, 53(2), pp.119-130.
  • Chan, M.P., Broadway, D.C., Khawaja, A.P., Yip, J.L., Garway-Heath, D.F., Burr, J.M., Luben, R., Hayat, S., Dalzell, N., Khaw, K.T. and Foster, P.J., 2017. Glaucoma and intraocular pressure in EPIC-Norfolk Eye Study: Cross sectional study. BMJ, 358, p.j3889.
  • Chantzichristos, D., Persson, A., Eliasson, B., Miftaraj, M., Franzén, S., Svensson, A.M. and Johannsson, G., 2018. Incidence, prevalence and seasonal onset variation of Addison’s disease among persons with type 1 diabetes mellitus: Nationwide, matched cohort studies. European Journal of Endocrinology, 178(1), pp.113-120.
  • Chen, Y., Dales, R. and Lin, M., 2003. The epidemiology of chronic rhinosinusitis in Canadians. The Laryngoscope, 113(7), pp.1199-1205.
  • Clemens, J.Q., Meenan, R.T., O’Keeffe Rosetti, M.C., Gao, S.Y. and Calhoun, E.A., 2005. Incidence and clinical characteristics of National Institutes of Health type III prostatitis in the community. The Journal of Urology, 174(6), pp.2319-2322.
  • Clifton, S., Fuller, E., and Philo, D., 2016. National Survey of Sexual Attitudes and Lifestyles (Natsal-3) Reference Tables. NatCen Social Research. Available from: http://www.natsal.ac.uk/media/3935/natsal-3-reference-tables.pdf
  • Collinson, D. and NatCen Social Research, 2016. Adult Psychiatric Morbidity Survey 2014, Chapter 2: Common Mental Disorders - Data Tables. NHS Digital.
  • Conolly, A., Saunders, C. and Neave, A., 2017. Health Survey for England 2016: Adult overweight and obesity Excel Tables. Leeds, UK: Health and Social Care Information Centre.
  • Cope, J.R., Collier, S.A., Rao, M.M., Chalmers, R., Mitchell, G.L., Richdale, K., Wagner, H., Kinoshita, B.T., Lam, D.Y., Sorbara, L. and Zimmerman, A., 2015. Contact lens wearer demographics and risk behaviors for contact lens-related eye infections—United States, 2014. MMWR: Morbidity and Mortality Weekly Report, 64(32), p.865.
  • Cramer, D.W., Xu, H. and Harlow, B.L., 1995. Family history as a predictor of early menopause. Fertility and Sterility, 64(4), pp.740-745.
  • Croft, P.R., Papageorgiou, A.C., Thomas, E., Macfarlane, G.J. and Silman, A.J., 1999. Short-term physical risk factors for new episodes of low back pain: Prospective evidence from the South Manchester Back Pain Study. Spine, 24(15), p.1556.
  • Czaja, C.A., Scholes, D., Hooton, T.M. and Stamm, W.E., 2007. Population-based epidemiologic analysis of acute pyelonephritis. Clinical Infectious Diseases, 45(3), pp.273-280.
  • Dahaghin, S., Bierma‐Zeinstra, S.M.A., Reijman, M., Pols, H.A.P., Hazes, J.M.W. and Koes, B.W., 2005. Does hand osteoarthritis predict future hip or knee osteoarthritis?. Arthritis & Rheumatism, 52(11), pp.3520-3527.
  • Dallosso, H., Matthews, R., McGrother, C. and Donaldson, M., 2004. Diet as a risk factor for the development of stress urinary incontinence: A longitudinal study in women. European Journal of Clinical Nutrition, 58(6), p.920.
  • de Graaf, R., Ten Have, M., van Gool, C. and van Dorsselaer, S., 2012. Prevalence of mental disorders and trends from 1996 to 2009. Results from the Netherlands Mental Health Survey and Incidence Study-2. Social Psychiatry and Psychiatric Epidemiology, 47(2), pp.203-213.
  • de Jonge, P., Roest, A.M., Lim, C.C., Florescu, S.E., Bromet, E.J., Stein, D.J., Harris, M., Nakov, V., Caldas‐de‐Almeida, J.M., Levinson, D. and Al‐Hamzawi, A.O., 2016. Cross‐national epidemiology of panic disorder and panic attacks in the world mental health surveys. Depression and Anxiety, 33(12), pp.1155-1177.
  • De Jonge, S., Van den Berg, C., De Vos, R.J., Van Der Heide, H.J.L., Weir, A., Verhaar, J.A.N., Bierma-Zeinstra, S.M.A. and Tol, J.L., 2011. Incidence of midportion Achilles tendinopathy in the general population. Br J Sports Med, 45(13), pp.1026-1028.
  • de Rijk, M., 1997. Epidemiology of Parkinson's Disease: The Rotterdam Study. Erasmus University Rotterdam.
  • de Voogd, S., Ikram, M.K., Wolfs, R.C., Jansonius, N.M., Hofman, A. and de Jong, P.T., 2005. Incidence of open-angle glaucoma in a general elderly population: The Rotterdam Study. Ophthalmology, 112(9), pp.1487-1493.
  • De Wit, M.A.S., Koopmans, M.P.G., Kortbeek, L.M., Wannet, W.J.B., Vinje, J., Van Leusden, F., Bartelds, A.I.M. and Van Duynhoven, Y.T.H.P., 2001. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: Incidence and etiology. American Journal of Epidemiology, 154(7), pp.666-674.
  • Des Varannes, S.B., Marek, L., Humeau, B., Lecasble, M. and Colin, R., 2006. Gastroesophageal reflux disease in primary care: Prevalence, epidemiology and quality of life of patients. Gastroentérologie Clinique et Biologique, 30(3), pp.364-370.
  • DeSimone, D.C., Tleyjeh, I.M., De Sa, D.D.C., Anavekar, N.S., Lahr, B.D., Sohail, M.R., Steckelberg, J.M., Wilson, W.R. and Baddour, L.M., 2015. Temporal trends in infective endocarditis epidemiology from 2007 to 2013 in Olmsted County, MN. American Heart Journal, 170(4), pp.830-836.
  • Ding, T., Baio, G., Hardiman, P.J., Petersen, I. and Sammon, C., 2016. Diagnosis and management of polycystic ovary syndrome in the UK (2004–2014): A retrospective cohort study. BMJ Open, 6(7), p.e012461.
  • Drey, N., Roderick, P., Mullee, M. and Rogerson, M., 2003. A population-based study of the incidence and outcomes of diagnosed chronic kidney disease. American Journal of Kidney Diseases, 42(4), pp.677-684.
  • Edvardsson, V.O., Indridason, O.S., Haraldsson, G., Kjartansson, O. and Palsson, R., 2013. Temporal trends in the incidence of kidney stone disease. Kidney International, 83(1), pp.146-152.
  • Egeberg, A., Kristensen, L.E., Thyssen, J.P., Gislason, G.H., Gottlieb, A.B., Coates, L.C., Jullien, D., Gisondi, P., Gladman, D.D., Skov, L. and Mallbris, L., 2017. Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study. Annals of the Rheumatic Diseases, 76(9), pp.1591-1597.
  • Erie, J.C., Hodge, D.O. and Gray, D.T., 1997. The incidence of primary angle-closure glaucoma in Olmsted County, Minnesota. Archives of Ophthalmology, 115(2), pp.177-181.
  • Evans, C.J., Fowkes, F.G.R., Ruckley, C.V. and Lee, A.J., 1999. Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study. Journal of Epidemiology & Community Health, 53(3), pp.149-153.
  • Exarchou, S., Lindström, U., Askling, J., Eriksson, J.K., Forsblad-d’Elia, H., Neovius, M., Turesson, C., Kristensen, L.E. and Jacobsson, L.T., 2015. The prevalence of clinically diagnosed ankylosing spondylitis and its clinical manifestations: A nationwide register study. Arthritis Research & Therapy, 17(1), p.118.
  • Farrand, K.F., Fridman, M., Stillman, I.Ö. and Schaumberg, D.A., 2017. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. American Journal of Ophthalmology, 182, pp.90-98.
  • Fernandez, A., Karavitaki, N. and Wass, J.A., 2010. Prevalence of pituitary adenomas: A community‐based, cross‐sectional study in Banbury (Oxfordshire, UK). Clinical Endocrinology, 72(3), pp.377-382.
  • Fleischmann, C., Thomas–Rueddel, D.O., Hartmann, M., Hartog, C.S., Welte, T., Heublein, S., Dennler, U. and Reinhart, K., 2016. Hospital incidence and mortality rates of sepsis: An analysis of hospital episode (DRG) statistics in Germany from 2007 to 2013. Deutsches Ärzteblatt International, 113(10), p.159.
  • Flynn, R.W.V., MacDonald, T.M., Morris, A.D., Jung, R.T. and Leese, G.P., 2004. The thyroid epidemiology, audit, and research study: Thyroid dysfunction in the general population. The Journal of Clinical Endocrinology & Metabolism, 89(8), pp.3879-3884.
  • Ford, A.C., Talley, N.J., Walker, M.M. and Jones, M.P., 2014. Increased prevalence of autoimmune diseases in functional gastrointestinal disorders: Case–control study of 23 471 primary care patients. Alimentary Pharmacology & Therapeutics, 40(7), pp.827-834.
  • Fox, K. and Rickards, L., 2004. Sport and Leisure: Results from the 2002 General Household Survey. Her Majesty's Stationery Office.
  • Frans, E.M., Sandin, S., Reichenberg, A., Lichtenstein, P., Långström, N. and Hultman, C.M., 2008. Advancing paternal age and bipolar disorder. Archives of General Psychiatry, 65(9), pp.1034-1040.
  • French, C.E., Hughes, G., Nicholson, A., Yung, M., Ross, J.D., Williams, T. and Soldan, K., 2011. Estimation of the rate of pelvic inflammatory disease diagnoses: Trends in England, 2000–2008. Sexually Transmitted Diseases, 38(3), pp.158-162.
  • Froehling, D.A., Silverstein, M.D., Mohr, D.N., Beatty, C.W., Offord, K.P., and Ballard, D.J., 1991. Benign positional vertigo: Incidence and prognosis in a population-based study in Olmsted County, Minnesota. In Mayo Clinic Proceedings (Vol. 66, No. 6, pp. 596-601). Elsevier.
  • Gandhi, M.M., Lampe, F.C. and Wood, D.A., 1995. Incidence, clinical characteristics, and short-term prognosis of angina pectoris. Heart, 73(2), pp.193-198.
  • Garraway, W.M., Lee, R.J. and Collins, G.N., 1991. High prevalence of benign prostatic hypertrophy in the community. The Lancet, 338(8765), pp.469-471.
  • Ghosh, R.E., Close, R., McCann, L.J., Crabbe, H., Garwood, K., Hansell, A.L. and Leonardi, G., 2015. Analysis of hospital admissions due to accidental non-fire-related carbon monoxide poisoning in England, between 2001 and 2010. Journal of Public Health, 38(1), pp.76-83.
  • Ghouri, N., Hippisley-Cox, J., Newton, J. and Sheikh, A., 2008. Trends in the epidemiology and prescribing of medication for allergic rhinitis in England. Journal of the Royal Society of Medicine, 101(9), pp.466-472.
  • Gittleman, H., Ostrom, Q.T., Farah, P.D., Ondracek, A., Chen, Y., Wolinsky, Y., Kruchko, C., Singer, J., Kshettry, V.R., Laws, E.R. and Sloan, A.E., 2014. Descriptive epidemiology of pituitary tumors in the United States, 2004–2009. Journal of Neurosurgery, 121(3), pp.527-535.
  • Grant, B.F., Goldstein, R.B., Chou, S.P., Huang, B., Stinson, F.S., Dawson, D.A., Saha, T.D., Smith, S.M., Pulay, A.J., Pickering, R.P. and Ruan, W.J., 2009. Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: Results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. Molecular Psychiatry, 14(11), p.1051.
  • Gritz, D.C. and Wong, I.G., 2004. Incidence and prevalence of uveitis in Northern California: The Northern California epidemiology of uveitis study. Ophthalmology, 111(3), pp.491-500.
  • Hall, G.C., Carroll, D., Parry, D. and McQuay, H.J., 2006. Epidemiology and treatment of neuropathic pain: The UK primary care perspective. Pain, 122(1-2), pp.156-162.
  • Harpaz, R., Dahl, R.M. and Dooling, K.L., 2016. Prevalence of immunosuppression among US adults, 2013. JAMA, 316(23), pp.2547-2548.
  • Harris, R.J., Ramsay, M., Hope, V.D., Brant, L., Hickman, M., Foster, G.R. and De Angelis, D., 2011. Hepatitis C prevalence in England remains low and varies by ethnicity: An updated evidence synthesis. The European Journal of Public Health, 22(2), pp.187-192.
  • Henderson, L., Bates, C., Farron, M., Gregory, J., Irving, K., Perks, J., Prentice, A. and Swan, G., 2003. The National Diet and Nutrition Survey: Adults Aged 19 to 64. Vitamin and Mineral Intake and Urinary Analytes. Her Majesty's Stationery Office.
  • Herrinton, L.J., Liu, L., Lewis, J.D., Griffin, P.M. and Allison, J., 2008. Incidence and prevalence of inflammatory bowel disease in a Northern California managed care organization, 1996–2002. The American Journal of Gastroenterology, 103(8), p.1998.
  • Hippisley-Cox, J. and Coupland, C., 2009. Predicting risk of osteoporotic fracture in men and women in England and Wales: Prospective derivation and validation of QFractureScores. BMJ, 339, p.b4229.
  • Hirji, I., Guo, Z., Andersson, S.W., Hammar, N. and Gomez-Caminero, A., 2012. Incidence of urinary tract infection among patients with type 2 diabetes in the UK General Practice Research Database (GPRD). Journal of Diabetes and its Complications, 26(6), pp.513-516.
  • Horsfall, L.J., Nazareth, I., Pereira, S.P. and Petersen, I., 2013. Gilbert's syndrome and the risk of death: A population‐based cohort study. Journal of Gastroenterology and Hepatology, 28(10), pp.1643-1647.
  • Howard, D.P., Banerjee, A., Fairhead, J.F., Hands, L., Silver, L.E. and Rothwell, P.M., 2015. Population-based study of incidence, risk factors, outcome, and prognosis of ischemic peripheral arterial events: Implications for prevention. Circulation, 132(19), pp.1805-1815.
  • Howard, P.J., Maher, L., Pryde, A., Cameron, E.W. and Heading, R.C., 1992. Five year prospective study of the incidence, clinical features, and diagnosis of achalasia in Edinburgh. Gut, 33(8), pp.1011-1015.
  • Hreinsson, J.P., Gumundsson, S., Kalaitzakis, E. and Björnsson, E.S., 2013. Lower gastrointestinal bleeding: Incidence, etiology, and outcomes in a population-based setting. European Journal of Gastroenterology & Hepatology, 25(1), pp.37-43.
  • Hughes, R.A., Charlton, J., Latinovic, R. and Gulliford, M.C., 2006. No association between immunization and Guillain-Barré syndrome in the United Kingdom, 1992 to 2000. Archives of Internal Medicine, 166(12), pp.1301-1304.
  • Humphreys, J.H., Verstappen, S.M., Hyrich, K.L., Chipping, J.R., Marshall, T. and Symmons, D.P., 2013. The incidence of rheumatoid arthritis in the UK: Comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register. Annals of the Rheumatic Diseases, 72(8), pp.1315-1320.
  • Ipsos MORI, 2016. Vegan Society Poll [online]. Ipsos MORI. [viewed 30 July 2018]. Available from: https://www.ipsos.com/ipsos-mori/en-uk/vegan-society-poll
  • Jeffery, A., Charman, S., Cosgriff, R., Carr, S., Ainsley, C., Gunn, E., Earlam, K. and Shi, M., 2017. UK Cystic Fibrosis Registry Annual Data Report 2016. UK Cystic Fibrosis Registry.
  • Jerrard-Dunne, P., Cloud, G., Hassan, A. and Markus, H.S., 2003. Evaluating the genetic component of ischemic stroke subtypes: A family history study. Stroke, 34(6), pp.1364-1369.
  • Johanson, J.F. and Sonnenberg, A., 1991. Temporal changes in the occurrence of hemorrhoids in the United States and England. Diseases of the Colon & Rectum, 34(7), pp.585-593.
  • Johansson, S., Wallander, M.A., Ruigómez, A. and Rodríguez, L.A.G., 2001. Incidence of newly diagnosed heart failure in UK general practice. European Journal of Heart Failure, 3(2), pp.225-231.
  • Jonsson, P., Hedenrud, T. and Linde, M., 2011. Epidemiology of medication overuse headache in the general Swedish population. Cephalalgia, 31(9), pp.1015-1022.
  • Jung, H.K., Locke III, G.R., Schleck, C.D., Zinsmeister, A.R., Szarka, L.A., Mullan, B. and Talley, N.J., 2009. The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006. Gastroenterology, 136(4), pp.1225-1233.
  • Khil, L., Pfaffenrath, V., Straube, A., Evers, S. and Berger, K., 2012. Incidence of migraine and tension-type headache in three different populations at risk within the German DMKG headache study. Cephalalgia, 32(4), pp.328-336.
  • Klossek, J.M., Neukirch, F., Pribil, C., Jankowski, R., Serrano, E., Chanal, I. and El Hasnaoui, A., 2005. Prevalence of nasal polyposis in France: A cross‐sectional, case–control study. Allergy, 60(2), pp.233-237.
  • Körner, H., Söndenaa, K., Söreide, J.A., Andersen, E., Nysted, A., Lende, T.H. and Kjellevold, K.H., 1997. Incidence of acute nonperforated and perforated appendicitis: Age-specific and sex-specific analysis. World Journal of Surgery, 21(3), pp.313-317.
  • Kornum, J.B., Christensen, S., Grijota, M., Pedersen, L., Wogelius, P., Beiderbeck, A. and Sørensen, H.T., 2008. The incidence of interstitial lung disease 1995–2005: A Danish nationwide population-based study. BMC Pulmonary Medicine, 8(1), p.24.
  • Kremers, H.M., Larson, D.R., Crowson, C.S., Kremers, W.K., Washington, R.E., Steiner, C.A., Jiranek, W.A. and Berry, D.J., 2015. Prevalence of total hip and knee replacement in the United States. The Journal of Bone and Joint Surgery. American Volume, 97(17), p.1386.
  • Kshettry, V.R., Hsieh, J.K., Ostrom, Q.T., Kruchko, C. and Barnholtz-Sloan, J.S., 2015. Incidence of vestibular schwannomas in the United States. Journal of Neuro-Oncology, 124(2), pp.223-228.
  • Kytö, V., Sipilä, J. and Rautava, P., 2014. Clinical profile and influences on outcomes in patients hospitalized for acute pericarditis. Circulation, 130(18), pp.1601-1606.
  • Kytö, V., Sipilä, J. and Rautava, P., 2015. Gender-specific and age-specific differences in unstable angina pectoris admissions: A population-based registry study in Finland. BMJ Open, 5(10), p.e009025.
  • Lane, D.A., Skjøth, F., Lip, G.Y., Larsen, T.B. and Kotecha, D., 2017. Temporal trends in incidence, prevalence, and mortality of atrial fibrillation in primary care. Journal of the American Heart Association, 6(5), p.e005155.
  • Lanting, R., van den Heuvel, E.R., Westerink, B. and Werker, P.M., 2013. Prevalence of Dupuytren disease in the Netherlands. Plastic and Reconstructive Surgery, 132(2), pp.394-403.
  • Lantto, I., Heikkinen, J., Flinkkilä, T., Ohtonen, P. and Leppilahti, J., 2015. Epidemiology of Achilles tendon ruptures: Increasing incidence over a 33‐year period. Scandinavian Journal of Medicine & Science in Sports, 25(1), pp.e133-e138.
  • Larsen, K. and Tos, M., 2002. The estimated incidence of symptomatic nasal polyps. Acta Oto-Laryngologica, 122(2), pp.179-182.
  • Latinovic, R., Gulliford, M.C. and Hughes, R.A.C., 2006. Incidence of common compressive neuropathies in primary care. Journal of Neurology, Neurosurgery & Psychiatry, 77(2), pp.263-265.
  • Lazo, M., Hernaez, R., Eberhardt, M.S., Bonekamp, S., Kamel, I., Guallar, E., Koteish, A., Brancati, F.L. and Clark, J.M., 2013. Prevalence of nonalcoholic fatty liver disease in the United States: The Third National Health and Nutrition Examination Survey, 1988–1994. American Journal of Epidemiology, 178(1), pp.38-45.
  • Looker, A.C., Dallman, P.R., Carroll, M.D., Gunter, E.W. and Johnson, C.L., 1997. Prevalence of iron deficiency in the United States. JAMA, 277(12), pp.973-976.
  • Los Angeles County Department of Public Health, 2016. Meningitis, Viral. Los Angeles County Department of Public Health. Available from: http://publichealth.lacounty.gov/acd/Diseases/Meningitis.pdf
  • Louis, E.D., Dogu, O. and Ottman, R., 2010. Subclinical tremor in normal controls with versus without a family history of essential tremor: Data from the United States and Turkey. European Journal of Neurology, 17(4), pp.607-611.
  • Lucenteforte, E., Talamini, R., Montella, M., Dal Maso, L., Pelucchi, C., Franceschi, S., La Vecchia, C. and Negri, E., 2009. Family history of cancer and the risk of endometrial cancer. European Journal of Cancer Prevention, 18(2), pp.95-99.
  • Ludvigsson, J.F., Rubio-Tapia, A., Van Dyke, C.T., Melton III, L.J., Zinsmeister, A.R., Lahr, B.D. and Murray, J.A., 2013. Increasing incidence of celiac disease in a North American population. The American Journal of Gastroenterology, 108(5), p.818.
  • Ma, X., Vanasse, G., Cartmel, B., Wang, Y. and Selinger, H.A., 2008. Prevalence of polycythemia vera and essential thrombocythemia. American Journal of Hematology, 83(5), pp.359-362.
  • Macfarlane, G.J., Beasley, M., Jones, E.A., Prescott, G.J., Docking, R., Keeley, P., McBeth, J., Jones, G.T. and MUSICIAN Study Team, 2012. The prevalence and management of low back pain across adulthood: Results from a population-based cross-sectional study (the MUSICIAN study). Pain, 153(1), pp.27-32.
  • Mackenzie, I.S., Morant, S.V., Bloomfield, G.A., MacDonald, T.M. and O'riordan, J., 2014. Incidence and prevalence of multiple sclerosis in the UK 1990–2010: A descriptive study in the General Practice Research Database. J Neurol Neurosurg Psychiatry, 85(1), pp.76-84.
  • Macmillan-NCIN Cancer Prevalence Project, 2015. 20-year cancer prevalence in the UK: By cancer site. Public Health England.
  • Mai, P.L., Wideroff, L., Greene, M.H. and Graubard, B.I., 2010. Prevalence of family history of breast, colorectal, prostate, and lung cancer in a population-based study. Public Health Genomics, 13(7-8), pp.495-503.
  • Majeed, A., Moser, K. and Carroll, K., 2001. Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994–1998: Analysis of data from the General Practice Research Database. Heart, 86(3), pp.284-288.
  • Maldini, C., Seror, R., Fain, O., Dhote, R., Amoura, Z., De Bandt, M., Delassus, J.L., Falgarone, G., Guillevin, L., Le Guern, V. and Lhote, F., 2014. Epidemiology of primary Sjögren's syndrome in a French multiracial/multiethnic area. Arthritis Care & Research, 66(3), pp.454-463.
  • Mallinson, P.I., Reagan, A.C., Coupal, T., Munk, P.L., Ouellette, H. and Nicolaou, S., 2014. The distribution of urate deposition within the extremities in gout: A review of 148 dual-energy CT cases. Skeletal Radiology, 43(3), pp.277-281.
  • Malvy, D., Ezzedine, K., Lancon, F., Halioua, B., Rezvani, A., Bertrais, S., Chanzy, B., Malkin, J.E., Morand, P., De Labareyre, C. and Hercberg, S., 2007. Epidemiology of orofacial herpes simplex virus infections in the general population in France: Results of the HERPIMAX study. Journal of the European Academy of Dermatology and Venereology, 21(10), pp.1398-1403.
  • Mapel, D.W., Schum, M. and Von Worley, A., 2014. The epidemiology and treatment of anal fissures in a population-based cohort. BMC Gastroenterology, 14(1), p.129.
  • Martín-Láez, R., Caballero-Arzapalo, H., Valle-San Román, N., López-Menéndez, L.Á., Arango-Lasprilla, J.C. and Vazquez-Barquero, A., 2016. Incidence of idiopathic normal-pressure hydrocephalus in Northern Spain. World Neurosurgery, 87, pp.298-310.
  • Martín-Merino, E., Wallander, M.A., Andersson, S., Soriano-Gabarró, M. and Rodríguez, L.A.G., 2016. The reporting and diagnosis of uterine fibroids in the UK: An observational study. BMC Women's Health, 16(1), p.45.
  • Martinez-Lapiscina, E.H., Fraga-Pumar, E., Pastor, X., Gómez, M., Conesa, A., Lozano-Rubi, R., Sánchez-Dalmau, B., Alonso, A. and Villoslada, P., 2014. Is the incidence of optic neuritis rising? Evidence from an epidemiological study in Barcelona (Spain), 2008–2012. Journal of Neurology, 261(4), pp.759-767.
  • Martinez, C., Wallenhorst, C., McFerran, D. and Hall, D.A., 2015. Incidence rates of clinically significant tinnitus: 10-year trend from a cohort study in England. Ear and Hearing, 36(3), p.e69.
  • Mathur, R., Douglas, I., Bhaskaran, K. and Smeeth, L., 2017. Diabetic eye disease: A UK Incidence and Prevalence Study. London School of Hygiene and Tropical Medicine.
  • Matthews, F.E., Arthur, A., Barnes, L.E., Bond, J., Jagger, C., Robinson, L., Brayne, C. and Medical Research Council Cognitive Function and Ageing Collaboration, 2013. A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: Results of the Cognitive Function and Ageing Study I and II. The Lancet, 382(9902), pp.1405-1412.
  • Matthews, F.E., Stephan, B.C.M., Robinson, L., Jagger, C., Barnes, L.E., Arthur, A., Brayne, C., Collaboration, A.S.C., Comas-Herrera, A., Wittenberg, R. and Dening, T., 2016. A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II. Nature Communications, 7, p.11398.
  • McLean, S., Hoogendoorn, M., Hoogenveen, R.T., Feenstra, T.L., Wild, S., Simpson, C.R., Rutten-van Mölken, M. and Sheikh, A., 2016. Projecting the COPD population and costs in England and Scotland: 2011 to 2030. Scientific Reports, 6, p.31893.
  • Mellemkjaer, L., Pfeiffer, R.M., Engels, E.A., Gridley, G., Wheeler, W., Hemminki, K., Olsen, J.H., Dreyer, L., Linet, M.S., Goldin, L.R. and Landgren, O., 2008. Autoimmune disease in individuals and close family members and susceptibility to non‐Hodgkin's lymphoma. Arthritis & Rheumatism, 58(3), pp.657-666.
  • Merinopoulou, E., Raluy-Callado, M., Ramagopalan, S., MacLachlan, S. and Khalid, J.M., 2016. COPD exacerbations by disease severity in England. International Journal of Chronic Obstructive Pulmonary Disease, 11, p.697.
  • Mitchell, P., Gopinath, B., Wang, J.J., McMahon, C.M., Schneider, J., Rochtchina, E. and Leeder, S.R., 2011. Five-year incidence and progression of hearing impairment in an older population. Ear and Hearing, 32(2), pp.251-257.
  • Mitry, D., Charteris, D.G., Yorston, D., Siddiqui, M.R., Campbell, H., Murphy, A.L., Fleck, B.W., Wright, A.F. and Singh, J., 2010. The epidemiology and socioeconomic associations of retinal detachment in Scotland: A two-year prospective population-based study. Investigative Ophthalmology & Visual Science, 51(10), pp.4963-4968.
  • Moore, M., Yuen, H.M., Dunn, N., Mullee, M.A., Maskell, J. and Kendrick, T., 2009. Explaining the rise in antidepressant prescribing: A descriptive study using the General Practice Research Database. BMJ, 339, p.b3999.
  • Moorman, J.E., Akinbami, L.J., Bailey, C.M., Zahran, H.S., King, M.E., Johnson, C.A. and Liu, X., 2012. National surveillance of asthma: United States, 2001-2010. Vital & Health Statistics. 3(35), pp.1-58.
  • Morales, D.R., Donnan, P.T., Daly, F., Van Staa, T. and Sullivan, F.M., 2013. Impact of clinical trial findings on Bell's palsy management in general practice in the UK 2001–2012: Interrupted time series regression analysis. BMJ Open, 3(7), p.e003121.
  • Morris, D.H., Jones, M.E., Schoemaker, M.J., Ashworth, A. and Swerdlow, A.J., 2010. Determinants of age at menarche in the UK: Analyses from the Breakthrough Generations Study. British Journal of Cancer, 103(11), p.1760.
  • Mozaffarian, D., Benjamin, E.J., Go, A.S., Arnett, D.K., Blaha, M.J., Cushman, M., De Ferranti, S., Després, J.P., Fullerton, H.J., Howard, V.J. and Huffman, M.D., 2015. Heart disease and stroke statistics—2015 update: A report from the American Heart Association. Circulation, 131(4), pp.434-441.
  • Muñoz, S.E., Ferraroni, M., La Vecchia, C. and Decarli, A., 1997. Gastric cancer risk factors in subjects with family history. Cancer Epidemiology and Prevention Biomarkers, 6(2), pp.137-140.
  • Næss, I.A., Christiansen, S.C., Romundstad, P., Cannegieter, S.C., Rosendaal, F.R. and Hammerstrøm, J., 2007. Incidence and mortality of venous thrombosis: A population‐based study. Journal of Thrombosis and Haemostasis, 5(4), pp.692-699.
  • Nannini, C., Jebakumar, A.J., Crowson, C.S., Ryu, J.H. and Matteson, E.L., 2013. Primary Sjögren's syndrome 1976–2005 and associated interstitial lung disease: A population-based study of incidence and mortality. BMJ Open, 3(11), p.e003569.
  • Nasir, K., Budoff, M.J., Wong, N.D., Scheuner, M., Herrington, D., Arnett, D.K., Szklo, M., Greenland, P. and Blumenthal, R.S., 2007. Family history of premature coronary heart disease and coronary artery calcification. Circulation, 116(6), pp.619-626.
  • NatCen Social Research and Neave, A., 2017. Health Survey for England 2016: Adult health trends Excel Tables. Leeds, UK: Health and Social Care Information Centre.
  • National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program. Table 12.7: Cancer of the Larynx (Invasive) [online]. National Cancer Institute [viewed 5 March 2018]. Available from: https://seer.cancer.gov/archive/csr/1975_2014/browse_csr.php?sectionSEL=12&pageSEL=sect_12_table.07.html
  • National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program. Table 20.8: Cancer of the Oral Cavity and Pharynx (Invasive) [online]. National Cancer Institute [viewed 5 March 2018]. Available from: https://seer.cancer.gov/archive/csr/1975_2014/browse_csr.php?sectionSEL=20&pageSEL=sect_20_table.08.html
  • Neave, A., 2016. Health Survey for England 2015 Trend Tables: Adult tables. Leeds, UK: Health and Social Care Information Centre.
  • Ng Fat, L. and Neave, A., 2016. Health Survey for England 2015: Adult cigarette smoking. Leeds, UK: Health and Social Care Information Centre.
  • Ng Fat, L., Mindell, J., Roderick, P. and Neave, A., 2017. Health Survey for England 2016: Kidney and liver disease. Leeds, UK: Health and Social Care Information Centre.
  • NHS Digital, 2017. Hospital admitted patient care activity, 2016–17. NHS Digital.
  • NHS Scotland, 2016. Breastfeeding Statistics Scotland. NHS Scotland Information Services Division.
  • Nicholson, A., Rait, G., Murray-Thomas, T., Hughes, G., Mercer, C.H. and Cassell, J., 2010. Management of epididymo-orchitis in primary care: Results from a large UK primary care database. Br J Gen Pract, 60(579), pp.e407-e422.
  • Noonan, V.K., Fingas, M., Farry, A., Baxter, D., Singh, A., Fehlings, M.G. and Dvorak, M.F., 2012. Incidence and prevalence of spinal cord injury in Canada: A national perspective. Neuroepidemiology, 38(4), pp.219-226.
  • Nordenskjöld, J., Englund, M., Zhou, C. and Atroshi, I., 2017. Prevalence and incidence of doctor-diagnosed Dupuytren’s disease: A population-based study. Journal of Hand Surgery (European Volume), 42(7), pp.673-677.
  • Nygaard, I., Barber, M.D., Burgio, K.L., Kenton, K., Meikle, S., Schaffer, J., Spino, C., Whitehead, W.E., Wu, J., Brody, D.J. and Pelvic Floor Disorders Network, 2008. Prevalence of symptomatic pelvic floor disorders in US women. JAMA, 300(11), pp.1311-1316.
  • Office for National Statistics, 2018. Conception Statistics, England and Wales 2016 [online]. Office for National Statistics. [viewed 29 May 2018]. Available from: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/conceptionandfertilityrates/datasets/conceptionstatisticsenglandandwalesreferencetables
  • Ogdie, A., Langan, S., Love, T., Haynes, K., Shin, D., Seminara, N., Mehta, N.N., Troxel, A., Choi, H. and Gelfand, J.M., 2012. Prevalence and treatment patterns of psoriatic arthritis in the UK. Rheumatology, 52(3), pp.568-575.
  • Oger, E. and EPI-GETBO study group, 2000. Incidence of venous thromboembolism: A community-based study in Western France. Thrombosis and Haemostasis, 83(05), pp.657-660.
  • Ohayon, M.M. and Roth, T., 2002. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. Journal of Psychosomatic Research, 53(1), pp.547-554.
  • Okike, I.O., Ribeiro, S., Ramsay, M.E., Heath, P.T., Sharland, M. and Ladhani, S.N., 2014. Trends in bacterial, mycobacterial, and fungal meningitis in England and Wales 2004–11: An observational study. The Lancet Infectious Diseases, 14(4), pp.301-307.
  • Okoroh, E.M., Hooper, W.C., Atrash, H.K., Yusuf, H.R. and Boulet, S.L., 2012. Prevalence of polycystic ovary syndrome among the privately insured, United States, 2003-2008. American Journal of Obstetrics and Gynecology, 207(4), pp.299-e1.
  • Oliveria, S.A., Felson, D.T., Reed, J.I., Cirillo, P.A. and Walker, A.M., 1995. Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization. Arthritis & Rheumatism, 38(8), pp.1134-1141.
  • Ostrom, Q.T., Gittleman, H., Liao, P., Vecchione-Koval, T., Wolinsky, Y., Kruchko, C. and Barnholtz-Sloan, J.S., 2017. CBTRUS statistical report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014. Neuro-Oncology, 19(suppl_5), pp.v1-v88.
  • Owen, C.G., Jarrar, Z., Wormald, R., Cook, D.G., Fletcher, A.E. and Rudnicka, A.R., 2012. The estimated prevalence and incidence of late stage age related macular degeneration in the UK. British Journal of Ophthalmology, 96(5), pp.752-756.
  • Paaso, E.M., Jaakkola, M.S., Rantala, A.K., Hugg, T.T. and Jaakkola, J.J., 2014. Allergic diseases and asthma in the family predict the persistence and onset-age of asthma: A prospective cohort study. Respiratory Research, 15(1), p.152.
  • Parkinson’s UK, 2017. The Incidence and Prevalence of Parkinson’s in the UK: Results from the Clinical Practice Research Datalink Reference Report. London: Parkinson's UK.
  • Parsons, S., Ingram, M., Clarke-Cornwell, A. and Symmons, D., 2011. A Heavy Burden: the occurrence and impact of musculoskeletal conditions in the United Kingdom today. Manchester UK: The University of Manchester.
  • Perälä, J., Suvisaari, J., Saarni, S.I., Kuoppasalmi, K., Isometsä, E., Pirkola, S., Partonen, T., Tuulio-Henriksson, A., Hintikka, J., Kieseppä, T. and Härkänen, T., 2007. Lifetime prevalence of psychotic and bipolar I disorders in a general population. Archives of General Psychiatry, 64(1), pp.19-28.
  • Phatak, P.D., Sham, R.L., Raubertas, R.F., Dunnigan, K., O'Leary, M.T., Braggins, C. and Cappuccio, J.D., 1998. Prevalence of hereditary hemochromatosis in 16 031 primary care patients. Annals of Internal Medicine, 129(11_Part_2), pp.954-961.
  • Plotnikoff, R., Karunamuni, N., Lytvyak, E., Penfold, C., Schopflocher, D., Imayama, I., Johnson, S.T. and Raine, K., 2015. Osteoarthritis prevalence and modifiable factors: A population study. BMC Public Health, 15(1), p.1195.
  • Pobereskin, L.H., 2001. Incidence and outcome of subarachnoid haemorrhage: A retrospective population based study. Journal of Neurology, Neurosurgery & Psychiatry, 70(3), pp.340-343.
  • Prieto-Alhambra, D., Judge, A., Javaid, M.K., Cooper, C., Diez-Perez, A. and Arden, N.K., 2014. Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: Influences of age, gender and osteoarthritis affecting other joints. Annals of the Rheumatic Diseases, 73(9), pp.1659-1664.
  • Public Health England National Infection Service, 2017. Table 2: New STI diagnoses & rates by gender, sexual risk & age group, 2013-2017. London: Public Health England.
  • Public Health England National Infection Service, 2017. Tuberculosis in England 2017 report (presenting data to end of 2016). London: Public Health England.
  • Public Health England National Infection Service, 2017. United Kingdom Country and PHE region HIV data tables. London: Public Health England.
  • Public Health England National Infection Service, 2018. United Kingdom National HIV surveillance data tables. London: Public Health England.
  • Public Health England, 2015. Laboratory reports of hepatitis A infection, and hepatitis C: 2015. Health Protection Report. 10(24).
  • Public Health England, 2017. Mumps: confirmed cases in England and Wales by age and region, 2012 to 2016 [online]. Public Health England. [viewed 30 April 2018]. Available from: https://www.gov.uk/government/publications/mumps-confirmed-cases/mumps-confirmed-cases-in-england-and-wales-by-age-and-region-2012-to-2013
  • Quinlan, K.P., Annest, J.L., Myers, B., Ryan, G. and Hill, H., 2004. Neck strains and sprains among motor vehicle occupants—United States, 2000. Accident Analysis & Prevention, 36(1), pp.21-27.
  • Quint, J.K., Millett, E.R., Joshi, M., Navaratnam, V., Thomas, S.L., Hurst, J.R., Smeeth, L. and Brown, J.S., 2016. Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: A population-based cohort study. European Respiratory Journal, 47(1), pp.186-193.
  • Rajkhowa, M., Glass, M.R., Rutherford, A.J., Balen, A.H., Sharma, V. and Cuckle, H.S., 2000. Trends in the incidence of ectopic pregnancy in England and Wales from 1966 to 1996. BJOG: An International Journal of Obstetrics & Gynaecology, 107(3), pp.369-374.
  • Raoof, N., Sharrack, B., Pepper, I.M. and Hickman, S.J., 2011. The incidence and prevalence of idiopathic intracranial hypertension in Sheffield, UK. European Journal of Neurology, 18(10), pp.1266-1268.
  • Ratib, S., West, J., Crooks, C.J. and Fleming, K.M., 2014. Diagnosis of liver cirrhosis in England, a cohort study, 1998–2009: A comparison with cancer. The American Journal of Gastroenterology. 109, pp.190-198.
  • Redburn, J.C. and Murphy, M.F.G., 2001. Hysterectomy prevalence and adjusted cervical and uterine cancer rates in England and Wales. BJOG: An International Journal of Obstetrics & Gynaecology, 108(4), pp.388-395.
  • Research & Surveillance Centre. Weekly Returns Service Annual Report 2015-2016. Royal College of General Practitioners.
  • Reynolds, S., Baden, P., Dhani, A., Bhagat, A., Tranter, M., Mais, D., and Wolch, E., 2017. Reported Road Casualties Great Britain: 2016. London: Department for Transport.
  • Roberts, S.E., Akbari, A., Thorne, K., Atkinson, M. and Evans, P.A., 2013. The incidence of acute pancreatitis: Impact of social deprivation, alcohol consumption, seasonal and demographic factors. Alimentary Pharmacology & Therapeutics, 38(5), pp.539-548.
  • Rodriguez, L.G., Ruigómez, A., Wallander, M.A., Johansson, S. and Olbe, L., 2000. Detection of colorectal tumor and inflammatory bowel disease during follow-up of patients with initial diagnosis of irritable bowel syndrome. Scandinavian Journal of Gastroenterology, 35(3), pp.306-311.
  • Ruigomez, A., Garcia Rodriguez, L.A., Wallander, M.A., Johansson, S., Graffner, H. and Dent, J., 2004. Natural history of gastro‐oesophageal reflux disease diagnosed in general practice. Alimentary Pharmacology & Therapeutics, 20(7), pp.751-760.
  • Sammon, C.J., Nazareth, I. and Petersen, I., 2016. Recording and treatment of premenstrual syndrome in UK general practice: A retrospective cohort study. BMJ Open, 6(3), p.e010244.
  • Sandhu, M.S., Luben, R. and Khaw, K.T., 2001. Prevalence and family history of colorectal cancer: Implications for screening. Journal of Medical Screening, 8(2), pp.69-72.
  • Scarborough, P., Peto, V., Bhatnagar, P., Kaur, A., Leal, J., Luengo-Fernandez, R., Gray, A., Rayner, M. and Allender, S.. Stroke Statistics 2009 Edition. British Heart Foundation.
  • Schoemaker, M.J., Swerdlow, A.J., Hepworth, S.J., McKinney, P.A., Van Tongeren, M. and Muir, K.R., 2006. History of allergies and risk of glioma in adults. International Journal of Cancer, 119(9), pp.2165-2172.
  • Scholes, S. and Neave, A., 2017. Health Survey for England 2016: Physical activity in adults Excel Tables. Leeds, UK: Health and Social Care Information Centre.
  • Seal, D.V., Kirkness, C.M., Bennett, H.G.B., Peterson, M. and Keratitis Study Group, 1999. Population-based cohort study of microbial keratitis in Scotland: Incidence and features. Contact Lens and Anterior Eye, 22(2), pp.49-57.
  • Shah, A., Judge, A., Delmestri, A., Edwards, K., Arden, N.K., Prieto-Alhambra, D., Holt, T.A., Pinedo-Villanueva, R.A., Hopewell, S., Lamb, S.E. and Rangan, A., 2017. Incidence of shoulder dislocations in the UK, 1995–2015: A population-based cohort study. BMJ Open, 7(11), p.e016112.
  • Sharma, A., Mukewar, S., Mara, K.C., Dierkhising, R.A., Kamath, P.S. and Cummins, N., 2018. Epidemiologic factors, clinical presentation, causes, and outcomes of liver abscess: A 35-Year Olmsted County study. Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2(1), pp.16-25.
  • Sharma, M., Nazareth, I. and Petersen, I., 2016. Trends in incidence, prevalence and prescribing in type 2 diabetes mellitus between 2000 and 2013 in primary care: A retrospective cohort study. BMJ Open, 6(1), p.e010210.
  • Silverberg, J.I. and Hanifin, J.M., 2013. Adult eczema prevalence and associations with asthma and other health and demographic factors: A US population–based study. Journal of Allergy and Clinical Immunology, 132(5), pp.1132-1138.
  • Smeeth, L., Cook, C. and Hall, A.J., 2006. Incidence of diagnosed polymyalgia rheumatica and temporal arteritis in the United Kingdom, 1990–2001. Annals of the Rheumatic Diseases, 65(8), pp.1093-1098.
  • Smolina, K., Wright, F.L., Rayner, M. and Goldacre, M.J., 2012. Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: National-linked database study. The European Journal of Public Health, 22(6), pp.848-853.
  • Song, J.Y., Schmit, P.T., Agreus, L., Kjellström, L., Nyhlin, H., Talley, N.J., and Andreasson, A.N.. Prevalence of Diverticular Disease in the General Population, and Link to Diarrhea but Not Constipation or the Irritable Bowel Syndrome [online]. AGA Abstracts. Available from: https://www.gastrojournal.org/article/S0016-5085(12)61693-X/pdf
  • Soriano, L.C., Rothenbacher, D., Choi, H.K. and Rodríguez, L.A.G., 2011. Contemporary epidemiology of gout in the UK general population. Arthritis Research & Therapy, 13(2), p.R39.
  • Steele, J. and O’Sullivan, A., 2011. Adult Dental Health Survey 2009—Summary report. London: National Health Service Health and Social Care Information Centre.
  • Steiner, T.J., Scher, A.I., Stewart, W.F., Kolodner, K., Liberman, J. and Lipton, R.B., 2003. The prevalence and disability burden of adult migraine in England and their relationships to age, gender and ethnicity. Cephalalgia, 23(7), pp.519-527.
  • Stochholm, K., Juul, S., Juel, K., Naeraa, R.W. and Højbjerg Gravholt, C., 2006. Prevalence, incidence, diagnostic delay, and mortality in Turner syndrome. The Journal of Clinical Endocrinology & Metabolism, 91(10), pp.3897-3902.
  • Suter, L.G., Murabito, J.M., Felson, D.T. and Fraenkel, L., 2005. The incidence and natural history of Raynaud's phenomenon in the community. Arthritis & Rheumatism, 52(4), pp.1259-1263.
  • Szentkiralyi, A., Fendrich, K., Hoffmann, W., Happe, S. and Berger, K., 2011. Incidence of restless legs syndrome in two population-based cohort studies in Germany. Sleep Medicine, 12(9), pp.815-820.
  • Templeman, C., Marshall, S.F., Ursin, G., Horn-Ross, P.L., Clarke, C.A., Allen, M., Deapen, D., Ziogas, A., Reynolds, P., Cress, R. and Anton-Culver, H., 2008. Adenomyosis and endometriosis in the California Teachers Study. Fertility and Sterility, 90(2), pp.415-424.
  • Thunander, M., Petersson, C., Jonzon, K., Fornander, J., Ossiansson, B., Torn, C., Edvardsson, S. and Landin-Olsson, M., 2008. Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden. Diabetes Research and Clinical Practice, 82(2), pp.247-255.
  • Tielsch, J.M., Katz, J., Sommer, A., Quigley, H.A. and Javitt, J.C., 1994. Family history and risk of primary open angle glaucoma: The Baltimore Eye Survey. Archives of Ophthalmology, 112(1), pp.69-73.
  • Townsend, N., Wickramasinghe, K., Bhatnagar, P., Smolina, K., Nichols, M., Leal, J., Luengo-Fernandez, R. and Rayner, M., 2012. Coronary heart disease statistics: A compendium of health statistics, 2012 edition. British Heart Foundation Health Promotion Research Group. Department of Public Health, University of Oxford.
  • Van Staa, T.P., Selby, P., Leufkens, H.G.M., Lyles, K., Sprafka, J.M. and Cooper, C., 2002. Incidence and natural history of Paget's disease of bone in England and Wales. Journal of Bone and Mineral Research, 17(3), pp.465-471.
  • van Zon, S.K., Snieder, H., Bültmann, U. and Reijneveld, S.A., 2017. The interaction of socioeconomic position and type 2 diabetes mellitus family history: A cross-sectional analysis of the Lifelines Cohort and Biobank Study. BMJ Open, 7(4), p.e015275.
  • Varghese, D., Saha, S., Scott, J.D., Chan, R.C. and McGrath, J.J., 2011. The association between family history of mental disorder and delusional‐like experiences: A general population study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 156(4), pp.478-483.
  • Veldhuis, J., Dieleman, J.P., Wohlfarth, T., Storosum, J.G., van Den Brink, W., Sturkenboom, M.C. and Denys, D., 2012. Incidence and prevalence of “diagnosed OCD” in a primary care, treatment seeking, population. International Journal of Psychiatry in Clinical Practice, 16(2), pp.85-92.
  • Verhamme, K.M.C., Dieleman, J.P., Bleumink, G.S., Van der Lei, J., Sturkenboom, M.C.J.M. and Panel, T.P.E.E., 2002. Incidence and prevalence of lower urinary tract symptoms suggestive of benign prostatic hyperplasia in primary care—the Triumph project. European Urology, 42(4), pp.323-328.
  • Vinogradova, Y., Coupland, C. and Hippisley-Cox, J., 2015. Use of combined oral contraceptives and risk of venous thromboembolism: Nested case-control studies using the QResearch and CPRD databases. BMJ, 350, p.h2135.
  • Walters, K., Rait, G., Griffin, M., Buszewicz, M. and Nazareth, I., 2012. Recent trends in the incidence of anxiety diagnoses and symptoms in primary care. PLoS One, 7(8), p.e41670.
  • West, J., Fleming, K.M., Tata, L.J., Card, T.R. and Crooks, C.J., 2014. Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: Population-based study. The American Journal of Gastroenterology, 109(5), p.757.
  • Weston, V.C., Jones, A.C., Bradbury, N., Fawthrop, F. and Doherty, M., 1999. Clinical features and outcome of septic arthritis in a single UK Health District 1982–1991. Annals of the Rheumatic Diseases, 58(4), pp.214-219.
  • White, D., Choi, H., Peloquin, C., Zhu, Y. and Zhang, Y., 2011. Secular trend of adhesive capsulitis. Arthritis Care & Research, 63(11), pp.1571-1575.
  • White, D., Pitts, N., Steele, J., Sadler, K. and Chadwick, B.L., 2011. Disease and related disorders–a report from the Adult Dental Health Survey 2009. The Health and Social Care Information Centre.
  • White, J.J.E., Titchener, A.G., Fakis, A., Tambe, A.A., Hubbard, R.B. and Clark, D.I., 2014. An epidemiological study of rotator cuff pathology using The Health Improvement Network database. The Bone & Joint Journal, 96(3), pp.350-353.
  • Williams, K.M., Verhoeven, V.J., Cumberland, P., Bertelsen, G., Wolfram, C., Buitendijk, G.H., Hofman, A., Van Duijn, C.M., Vingerling, J.R., Kuijpers, R.W. and Höhn, R., 2015. Prevalence of refractive error in Europe: The European Eye Epidemiology (E3) Consortium. European Journal of Epidemiology, 30(4), pp.305-315.
  • Wilson, S., Roberts, L., Roalfe, A., Bridge, P. and Singh, S., 2004. Prevalence of irritable bowel syndrome: A community survey. Br J Gen Pract, 54(504), pp.495-502.
  • Wright, N.C., Looker, A.C., Saag, K.G., Curtis, J.R., Delzell, E.S., Randall, S. and Dawson‐Hughes, B., 2014. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. Journal of Bone and Mineral Research, 29(11), pp.2520-2526.
  • Wu, J. and Morris, J.K., 2013. The population prevalence of Down’s syndrome in England and Wales in 2011. European Journal of Human Genetics, 21(9), p.1016.
  • Xu, L., Li, G., Wei, Q., El‐Naggar, A.K. and Sturgis, E.M., 2012. Family history of cancer and risk of sporadic differentiated thyroid carcinoma. Cancer, 118(5), pp.1228-1235.
  • Yadav, D., Timmons, L., Benson, J.T., Dierkhising, R.A. and Chari, S.T., 2011. Incidence, prevalence, and survival of chronic pancreatitis: A population-based study. The American Journal of Gastroenterology, 106(12), p.2192.
  • Zarrinkoub, R., Wettermark, B., Wändell, P., Mejhert, M., Szulkin, R., Ljunggren, G. and Kahan, T., 2013. The epidemiology of heart failure, based on data for 2.1 million inhabitants in Sweden. European Journal of Heart Failure, 15(9), pp.995-1002.
  • Zhu, Y., Pandya, B.J. and Choi, H.K., 2011. Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007–2008. Arthritis & Rheumatism, 63(10), pp.3136-3141.

Healthcheck

  • Andres, E. and Serraj, K., 2012. Optimal management of pernicious anemia. Journal of Blood Medicine, 3, p.97.
  • Anstey, K.J., von Sanden, C., Salim, A. and O'kearney, R., 2007. Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies. American Journal of Epidemiology, 166(4), pp.367-378.
  • Antonelli, A., Mosca, M., Fallahi, P., Neri, R., Ferrari, S.M., D'ascanio, A., Ghiri, E., Carli, L., Miccoli, P. and Bombardieri, S., 2010. Thyroid cancer in systemic lupus erythematosus: a case-control study. The Journal of Clinical Endocrinology & Metabolism, 95(1), pp.314-318.
  • Badley, E.M. and Tennant, A., 1992. Changing profile of joint disorders with age: findings from a postal survey of the population of Calderdale, West Yorkshire, United Kingdom. Annals of the Rheumatic Diseases, 51(3), pp.366-371.
  • Bansal, N., Fischbacher, C.M., Bhopal, R.S., Brown, H., Steiner, M.F., Capewell, S. and Scottish Health and Ethnicity Linkage Study, 2013. Myocardial infarction incidence and survival by ethnic group: Scottish Health and Ethnicity Linkage retrospective cohort study. BMJ Open, 3(9), p.e003415.
  • Barbanti, P., Fabbrini, G., Aurilia, C., Vanacore, N. and Cruccu, G., 2007. A case–control study on excessive daytime sleepiness in episodic migraine. Cephalalgia, 27(10), pp.1115-1119.
  • Barnes, D.E. and Yaffe, K., 2011. The projected effect of risk factor reduction on Alzheimer's disease prevalence. The Lancet Neurology, 10(9), pp.819-828.
Bates, B., Lennox, A., Prentice, A., Bates, C.J., Page, P., Nicholson, S. and Swan, G. eds., 2014. National Diet and Nutrition Survey: Results from Years 1, 2, 3 and 4 (combined) of the Rolling Programme (2008/2009-2011/2012): a Survey Carried Out on Behalf of Public Health England and the Food Standards Agency. Public Health England.
  • Becker, U., Grønbæk, M., Johansen, D. and Sørensen, T.I., 2002. Lower risk for alcohol‐induced cirrhosis in wine drinkers. Hepatology, 35(4), pp.868-875.
  • Beekman, A.T., Bremmer, M.A., Deeg, D.J., Van Balkom, A.J.L.M., Smit, J.H., De Beurs, E., Van Dyck, R. and Van Tilburg, W., 1998. Anxiety disorders in later life: a report from the Longitudinal Aging Study Amsterdam. International Journal of Geriatric Psychiatry, 13(10), pp.717-726.
  • Beekman, A.T., Deeg, D.J., van Tilburg, T., Smit, J.H., Hooijer, C. and van Tilburg, W., 1995. Major and minor depression in later life: a study of prevalence and risk factors. Journal of Affective Disorders, 36(1), pp.65-75.
  • Bertuzzi, M., Negri, E., Tavani, A. and La Vecchia, C., 2003. Family history of ischemic heart disease and risk of acute myocardial infarction. Preventive Medicine, 37(3), pp.183-187.
  • Blanco, C., Okuda, M., Markowitz, J.C., Liu, S.M., Grant, B.F. and Hasin, D.S., 2010. The epidemiology of chronic major depressive disorder and dysthymic disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. The Journal of Clinical Psychiatry, 71(12), p.1645.
  • Boelaert, K., Newby, P.R., Simmonds, M.J., Holder, R.L., Carr-Smith, J.D., Heward, J.M., Manji, N., Allahabadia, A., Armitage, M., Chatterjee, K.V. and Lazarus, J.H., 2010. Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease. The American Journal of Medicine, 123(2), pp.183-e1.
  • Botterweck, A.A., van den Brandt, P.A. and Goldbohm, R.A., 1998. A prospective cohort study on vegetable and fruit consumption and stomach cancer risk in The Netherlands. American Journal of Epidemiology, 148(9), pp.842-853.
  • Bouvy, M.L., Heerdink, E.R., Hoes, A.W. and Leufkens, H.G., 2002. Amiodarone‐induced thyroid dysfunction associated with cumulative dose. Pharmacoepidemiology and Drug Safety, 11(7), pp.601-606.
  • Bradford-ONS, S., 2012. Ethnicity and National Identity in England and Wales 2011.
  • Busch, M., Maske, U., Ryl, L., Schlack, R. and Hapke, U., 2013. Prevalence of depressive symptoms and diagnosed depression among adults in Germany.
  • Cappuccio, F.P., D'elia, L., Strazzullo, P. and Miller, M.A., 2010. Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis. Diabetes care, 33(2), pp.414-420.
  • Cassidy, A., Myles, J.P., Duffy, S.W., Liloglou, T. and Field, J.K., 2006. Family history and risk of lung cancer: age-at-diagnosis in cases and first-degree relatives. British Journal of Cancer, 95(9), p.1288.
  • Chazelle, E., Lemogne, C., Morgan, K., Kelleher, C.C., Chastang, J.F. and Niedhammer, I., 2011. Explanations of educational differences in major depression and generalised anxiety disorder in the Irish population. Journal of Affective Disorders, 134(1), pp.304-314.
  • Coggon, D., Reading, I., Croft, P., McLaren, M., Barrett, D. and Cooper, C., 2001. Knee osteoarthritis and obesity. International Journal of Obesity & Related Metabolic Disorders, 25(5).
  • Cohen, S., Kamarck, T. and Mermelstein, R., 1983. A global measure of perceived stress. Journal of Health and Social Behavior, pp.385-396.
  • Community and Mental Health Team NHS Digital, 2016. Maternity Services Monthly Statistics Report: Reference Data Tables, July 2016.
  • Cooper, C., McAlindon, T., Snow, S., Vines, K., Young, P., Kirwan, J. and Dieppe, P., 1994. Mechanical and constitutional risk factors for symptomatic knee osteoarthritis: differences between medial tibiofemoral and patellofemoral disease. The Journal of Rheumatology, 21(2), pp.307-313.
  • Corrao, G., Arico, S., Zambon, A., Torchio, P. and Orio, F.D., 1997. Female sex and the risk of liver cirrhosis. Scandinavian Journal of Gastroenterology, 32(11), pp.1174-1180.
  • Coté, M.L., Liu, M., Bonassi, S., Neri, M., Schwartz, A.G., Christiani, D.C., Spitz, M.R., Muscat, J.E., Rennert, G., Aben, K.K. and Andrew, A.S., 2012. Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. European Journal of Cancer, 48(13), pp.1957-1968.
  • Dahaghin, S., Bierma‐Zeinstra, S.M.A., Reijman, M., Pols, H.A.P., Hazes, J.M.W. and Koes, B.W., 2005. Does hand osteoarthritis predict future hip or knee osteoarthritis?. Arthritis & Rheumatism, 52(11), pp.3520-3527.
  • De Marco, R., Accordini, S., Cerveri, I., Corsico, A., Sunyer, J., Neukirch, F., Künzli, N., Leynaert, B., Janson, C., Gislason, T. and Vermeire, P., 2004. An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages. Thorax, 59(2), pp.120-125.
  • Diamond, C., Thiede, H., Perdue, T., Secura, G.M., Valleroy, L., Mackellar, D. and Corey, L., 2003. Viral hepatitis among young men who have sex with men: prevalence of infection, risk behaviors, and vaccination. Sexually Transmitted Diseases, 30(5), pp.425-432.
  • EBM DataLab, Department of Primary Care Health Sciences, University of Oxford, 2017. OpenPrescribing: Aspirin.
  • EBM DataLab, Department of Primary Care Health Sciences, University of Oxford, 2017. OpenPrescribing: Lithium Carbonate.
  • EBM DataLab, Department of Primary Care Health Sciences, University of Oxford, 2017. OpenPrescribing: Lithium Citrate.
  • Enroth, H., Kraaz, W., Engstrand, L., Nyrén, O. and Rohan, T., 2000. Helicobacter pylori strain types and risk of gastric cancer: a case-control study. Cancer Epidemiology and Prevention Biomarkers, 9(9), pp.981-985.
  • Erens, B., Phelps, A., Clifton, S., Mercer, CH., Tanton, C., Hussey, D., Sonnenber, P., Macdowall, W., Field, N., Datta, J., Mitchell, K., Copas, AJ., Wellings, K., Johnson, AM., 2014. National Survey of Sexual Attitudes and Lifestyles (Natsal-3) Reference tables.
  • Fenton, K.A., Korovessis, C., Johnson, A.M., McCadden, A., McManus, S., Wellings, K., Mercer, C.H., Carder, C., Copas, A.J., Nanchahal, K. and Macdowall, W., 2001. Sexual behaviour in Britain: reported sexually transmitted infections and prevalent genital Chlamydia trachomatis infection. The Lancet, 358(9296), pp.1851-1854.
  • Fitt, E., Pell, D. and Cole, D., 2013. Assessing caffeine intake in the United Kingdom diet. Food Chemistry, 140(3), pp.421-426.
  • Flynn, R.W.V., MacDonald, T.M., Morris, A.D., Jung, R.T. and Leese, G.P., 2004. The thyroid epidemiology, audit, and research study: thyroid dysfunction in the general population. The Journal of Clinical Endocrinology & Metabolism, 89(8), pp.3879-3884.
  • Foschi, R., Lucenteforte, E., Bosetti, C., Bertuccio, P., Tavani, A., La Vecchia, C. and Negri, E., 2008. Family history of cancer and stomach cancer risk. International Journal of Cancer, 123(6), pp.1429-1432.
  • Frisell, T., Holmqvist, M., Källberg, H., Klareskog, L., Alfredsson, L. and Askling, J., 2013. Familial risks and heritability of rheumatoid arthritis: role of rheumatoid factor/anti–citrullinated protein antibody status, number and type of affected relatives, sex, and age. Arthritis & Rheumatology, 65(11), pp.2773-2782.
  • Garcia Rodriguez, L.A., Tolosa, L.B., Ruigomez, A., Johansson, S. and Wallander, M.A., 2009. Rheumatoid arthritis in UK primary care: incidence and prior morbidity. Scandinavian Journal of Rheumatology, 38(3), pp.173-177.
  • Garfein, R.S., Vlahov, D., Galai, N., Doherty, M.C. and Nelson, K.E., 1996. Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses. American Journal of Public Health, 86(5), pp.655-661.
  • Gavin, N.I., Gaynes, B.N., Lohr, K.N., Meltzer-Brody, S., Gartlehner, G. and Swinson, T., 2005. Perinatal depression: a systematic review of prevalence and incidence. Obstetrics & Gynecology, 106(5, Part 1), pp.1071-1083.
  • Gelber, A.C., Hochberg, M.C., Mead, L.A., Wang, N.Y., Wigley, F.M. and Klag, M.J., 2000. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Annals of Internal Medicine, 133(5), pp.321-328.
  • Gerlich, M.G., Krämer, A., Gmel, G., Maggiorini, M., Lüscher, T.F., Rickli, H., Kleger, G.R. and Rehm, J., 2009. Patterns of alcohol consumption and acute myocardial infarction: a case-crossover analysis. European Addiction Research, 15(3), pp.143-149.
  • Gibson, J.J., Hornung, C.A., Alexander, G.R., Lee, F.K., Potts, W.A. and Nahmias, A.J., 1990. A cross-sectional study of herpes simplex virus types 1 and 2 in college students: occurrence and determinants of infection. Journal of Infectious Diseases, 162(2), pp.306-312.
  • Gilkes, A., Hull, S., Durbaba, S., Schofield, P., Ashworth, M., Mathur, R. and White, P., 2017. Ethnic differences in smoking intensity and COPD risk: an observational study in primary care. NPJ Primary Care Respiratory Medicine, 27(1), p.50.
  • Giorda, C.B., Carnà, P., Romeo, F., Costa, G., Tartaglino, B. and Gnavi, R., 2017. Prevalence, incidence and associated comorbidities of treated hypothyroidism: an update from a European population. European Journal of Endocrinology, 176(5), pp.533-542.
  • Grant, B.F., Goldstein, R.B., Chou, S.P., Huang, B., Stinson, F.S., Dawson, D.A., Saha, T.D., Smith, S.M., Pulay, A.J., Pickering, R.P. and Ruan, W.J., 2009. Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. Molecular Psychiatry, 14(11), pp.1051-1066.
  • Hagen, K., Thoresen, K., Stovner, L.J. and Zwart, J.A., 2009. High dietary caffeine consumption is associated with a modest increase in headache prevalence: results from the Head-HUNT Study. The Journal of Headache and Pain, 10(3), pp.153-159.
  • Hajat, C., Heuschmann, P.U., Coshall, C., Padayachee, S., Chambers, J., Rudd, A.G. and Wolfe, C.D., 2010. Incidence of aetiological subtypes of stroke in a multi-ethnic population based study: the South London Stroke Register. Journal of Neurology, Neurosurgery & Psychiatry, pp.jnnp-2010.
  • Hajat, C., Tilling, K., Stewart, J.A., Lemic-Stojcevic, N. and Wolfe, C.D., 2004. Ethnic differences in risk factors for ischemic stroke. Stroke, 35(7), pp.1562-1567.
  • Hay, G., Santos, A. R., Worsley, J., Estimates of Prevalence of Opiate Use and/or Crack Cocaine Use, 2011/12: Sweep 8 report.
  • Health and Social Care Information Centre, 2017. Health Survey for England 2016: Adult health trends. Excel tables
  • Health and Social Care Information Centre, 2017. Health Survey for England 2016: Adult overweight and obesity: Excel tables
  • Health and Social Care Information Centre, 2017. Health Survey for England 2016: Physical Activity in Adults: Excel tables Health and Social Care Information Centre,2012. Health Survey for England 2011: Health, social care and lifestyles.
  • Hennekens, C.H., 1989. Final report on the aspirin component of the ongoing Physicians Health Study. New England Journal of Medicine, 321(3), pp.129-135.
  • Hinz, A., Glaesmer, H., Brähler, E., Löffler, M., Engel, C., Enzenbach, C., Hegerl, U. and Sander, C., 2017. Sleep quality in the general population: psychometric properties of the pittsburgh sleep quality index, derived from a german community sample of 9284 people. Sleep Medicine, 30, pp.57-63.
  • Hippisley-Cox, J. and Coupland, C., 2009. Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScores. BMJ, 339, p.b4229.
  • Hippisley-Cox, J. and Coupland, C., 2012. Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study. BMJA, 344, p.e3427.
  • Hippisley-Cox, J., Coupland, C., Robson, J., Sheikh, A. and Brindle, P., 2009. Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScore. Bmj, 338, p.b880.
Holley-Moore, G. and Beach, B., 2016. Drink wise, age well: alcohol use and the over 50s in the UK.
  • House of Commons Home Affairs Committee, 2016. Prostitution: Third Report of Session 2016-17.
  • Hughes, G., Catchpole, M., Rogers, P.A., Brady, A.R., Kinghorn, G., Mercey, D. and Thin, N., 2000. Comparison of risk factors for four sexually transmitted infections: results from a study of attenders at three genitourinary medicine clinics in England. Sexually Transmitted Infections, 76(4), pp.262-267.
  • Hylek, E.M. and Singer, D.E., 1994. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Annals of Internal Medicine, 120(11), pp.897-902.
  • Institute for Health Metrics and Evaluation, 2016
  • Jacobs, E.J., Thun, M.J., Bain, E.B., Rodriguez, C., Henley, S.J. and Calle, E.E., 2007. A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence. Journal of the National Cancer Institute, 99(8), pp.608-615.
  • Janciauskiene, S.M., Bals, R., Koczulla, R., Vogelmeier, C., Köhnlein, T. and Welte, T., 2011. The discovery of α1-antitrypsin and its role in health and disease. Respiratory Medicine, 105(8), pp.1129-1139. Järvenpää, T., Rinne, J.O., Koskenvuo, M., Räihä, I. and Kaprio, J., 2005. Binge drinking in midlife and dementia risk. Epidemiology, 16(6), pp.766-771.
  • Jerrard-Dunne, P., Cloud, G., Hassan, A. and Markus, H.S., 2003. Evaluating the genetic component of ischemic stroke subtypes. Stroke, 34(6), pp.1364-1369. Johnston, A.M. and Eagles, J.M., 1999. Lithium-associated clinical hypothyroidism. Prevalence and risk factors. The British Journal of Psychiatry, 175(4), pp.336-339.
  • Jood, K., Ladenvall, C., Rosengren, A., Blomstrand, C. and Jern, C., 2005. Family history in ischemic stroke before 70 years of age. Stroke, 36(7), pp.1383-1387.
  • Juhakoski, R., Heliövaara, M., Impivaara, O., Kröger, H., Knekt, P., Lauren, H. and Arokoski, J.P.A., 2008. Risk factors for the development of hip osteoarthritis: a population-based prospective study. Rheumatology, 48(1), pp.83-87.
  • Juvela, S., Hillbom, M. and Palomäki, H., 1995. Risk factors for spontaneous intracerebral hemorrhage. Stroke, 26(9), pp.1558-1564.
  • Kalmijn, S., Launer, L.J., Ott, A., Witteman, J., Hofman, A. and Breteler, M., 1997. Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Annals of Neurology, 42(5), pp.776-782. Kanis, J.A., Borgstrom, F., De Laet, C., Johansson, H., Johnell, O., Jonsson, B., Oden, A., Zethraeus, N., Pfleger, B. and Khaltaev, N., 2005. Assessment of fracture risk. Osteoporosis International, 16(6), pp.581-589.
  • Kanis, J.A., Johansson, H., Johnell, O., Oden, A., De Laet, C., Eisman, J.A., Pols, H. and Tenenhouse, A., 2005. Alcohol intake as a risk factor for fracture. Osteoporosis International, 16(7), pp.737-742.
  • Kanis, J.A., Johnell, O., Odén, A., Johansson, H., De Laet, C., Eisman, J.A., Fujiwara, S., Kroger, H., McCloskey, E.V., Mellstrom, D. and Melton, L.J., 2005. Smoking and fracture risk: a meta-analysis. Osteoporosis International, 16(2), pp.155-162.
  • Kernan, W.N., Viscoli, C.M., Brass, L.M., Broderick, J.P., Brott, T., Feldmann, E., Morgenstern, L.B., Wilterdink, J.L. and Horwitz, R.I., 2000. Phenylpropanolamine and the risk of hemorrhagic stroke. New England Journal of Medicine, 343(25), pp.1826-1832.
  • Kersting, A., Brähler, E., Glaesmer, H. and Wagner, B., 2011. Prevalence of complicated grief in a representative population-based sample. Journal of Affective Disorders, 131(1), pp.339-343.
  • Kim, C.H., Lee, Y.C.A., Hung, R.J., McNallan, S.R., Cote, M.L., Lim, W.Y., Chang, S.C., Kim, J.H., Ugolini, D., Chen, Y. and Liloglou, T., 2014. Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). International Journal of Cancer, 135(8), pp.1918-1930.
Klatsky, A.L., Friedman, G.D., Sidney, S., Kipp, H., Kubo, A. and Armstrong, M.A., 2005. Risk of hemorrhagic stroke in Asian American ethnic groups. Neuroepidemiology, 25(1), pp.26-31.
  • Kraïm-Leleu, M., Lesage, F.X., Drame, M., Lebargy, F. and Deschamps, F., 2016. Occupational risk factors for COPD: a case-control study. PloS One, 11(8), p.e0158719.
  • Kroenke, K., Spitzer, R.L. and Williams, J.B., 2003. The Patient Health Questionnaire-2: validity of a two-item depression screener. Medical Care, 41(11), pp.1284-1292.
  • Kumari, M., Head, J. and Marmot, M., 2004. Prospective study of social and other risk factors for incidence of type 2 diabetes in the Whitehall II study. Archives of internal medicine, 164(17), pp.1873-1880. Lamote de Grignon Pérez, J., Gershuny, J., Foster, R. and De Vos, M., 2018. Sleep differences in the UK between 1974 and 2015: Insights from detailed time diaries. Journal of sleep research, p.e12753.
  • Lin, S.Y., Chang, E.T. and So, S.K., 2007. Why we should routinely screen Asian American adults for hepatitis B: a cross‐sectional study of Asians in California. Hepatology, 46(4), pp.1034-1040.
  • Lindblad, M., Rodríguez, L.A.G. and Lagergren, J., 2005. Body mass, tobacco and alcohol and risk of esophageal, gastric cardia, and gastric non-cardia adenocarcinoma among men and women in a nested case-control study. Cancer Causes & Control, 16(3), pp.285-294.
  • Lubin, J.H. and Boice Jr, J.D., 1997. Lung cancer risk from residential radon: meta-analysis of eight epidemiologic studies. Journal of the National Cancer Institute, 89(1), pp.49-57.
  • Luppino, F.S., de Wit, L.M., Bouvy, P.F., Stijnen, T., Cuijpers, P., Penninx, B.W. and Zitman, F.G., 2010. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Archives of General Psychiatry, 67(3), pp.220-229.
  • Lyngberg, A.C., Rasmussen, B.K., Jørgensen, T. and Jensen, R., 2005. Incidence of primary headache: a Danish epidemiologic follow-up study. American Journal of Epidemiology, 161(11), pp.1066-1073.
  • Lyssenko, V., Jonsson, A., Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P. and Groop, L., 2008. Clinical risk factors, DNA variants, and the development of type 2 diabetes. New England Journal of Medicine, 359(21), pp.2220-2232.
  • Mahler, B., Carlsson, S., Andersson, T., Adelöw, C., Ahlbom, A. and Tomson, T., 2015. Unprovoked seizures after traumatic brain injury: A population‐based case–control study. Epilepsia, 56(9), pp.1438-1444.
  • Mai, P.L., Wideroff, L., Greene, M.H. and Graubard, B.I., 2010. Prevalence of family history of breast, colorectal, prostate, and lung cancer in a population-based study. Public health genomics, 13(7-8), pp.495-503.
  • Majeed, A., Moser, K. and Carroll, K., 2001. Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994–1998: analysis of data from the general practice research database. Heart, 86(3), pp.284-288.
  • Manhart, L.E., Aral, S.O., Holmes, K.K., Critchlow, C.W., Hughes, J.P., Whittington, W.L. and Foxman, B., 2004. Influence of study population on the identification of risk factors for sexually transmitted diseases using a case-control design: the example of gonorrhea. American Journal of Epidemiology, 160(4), pp.393-402.
  • Mc Grath-Lone, L., Marsh, K., Hughes, G. and Ward, H., 2014. The sexual health of female sex workers compared with other women in England: analysis of cross-sectional data from genitourinary medicine clinics. Sexually Transmitted Infections, pp.sextrans-2013.
  • McLaughlin, K.A., Behar, E. and Borkovec, T.D., 2008. Family history of psychological problems in generalized anxiety disorder. Journal of Clinical Psychology, 64(7), pp.905-918.
  • McQuillan, G.M., Coleman, P.J., Kruszon-Moran, D., Moyer, L.A., Lambert, S.B. and Margolis, H.S., 1999. Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994. American Journal of Public Health, 89(1), pp.14-18.
  • Mellemkjaer, L., Pfeiffer, R.M., Engels, E.A., Gridley, G., Wheeler, W., Hemminki, K., Olsen, J.H., Dreyer, L., Linet, M.S., Goldin, L.R. and Landgren, O., 2008. Autoimmune disease in individuals and close family members and susceptibility to non‐Hodgkin's lymphoma. Arthritis & Rheumatology, 58(3), pp.657-666.
  • Morris Rosenberg, Ph.D. (deceased) Rosenberg, M.,1965. Society and The Adolescent Self-Image. Princeton, N.J.: Princeton University Press.
  • Muñoz, S.E., Ferraroni, M., La Vecchia, C. and Decarli, A., 1997. Gastric cancer risk factors in subjects with family history. Cancer Epidemiology and Prevention Biomarkers, 6(2), pp.137-140.
  • Murphy, G., Dawsey, S.M., Engels, E.A., Ricker, W., Parsons, R., Etemadi, A., Lin, S.W., Abnet, C.C. and Freedman, N.D., 2015. Cancer risk after pernicious anemia in the US elderly population. Clinical Gastroenterology and Hepatology, 13(13), pp.2282-2289.
  • Nacul, L.C., Soljak, M. and Meade, T., 2007. Model for estimating the population prevalence of chronic obstructive pulmonary disease: cross sectional data from the Health Survey for England. Population Health Metrics, 5(1), p.8.
  • NHS Digital, 2017. National Diabetes Audit 2015-2016. Report 1- Supplementary Information: National Summary: Table and Charts.
  • Nickolas, T.L., McMahon, D.J. and Shane, E., 2006. Relationship between moderate to severe kidney disease and hip fracture in the United States. Journal of the American Society of Nephrology, 17(11), pp.3223-3232.
  • Office for National Statistics, 2002. The National Diet & Nutrition Survey: adults aged 19 to 64 years. Types and quantities of food consumed. Office for National Statistics, 2011. 2011 Census Analysis- Comparing Rural and Urban Areas of England and Wales.
  • Office for National Statistics, 2012. First ONS Annual Experimental Subjective Well-being Results.
  • Office for National Statistics, 2017. EMP04: Employment by occupation.
  • Office for National Statistics, 2017. Labour Force Survey Summary: People by economic activity for those aged 16 and over and those aged from 16 to 64 (not seasonally adjusted).
  • Office for National Statistics, 2017. Population Estimates. United Kingdom population mid-year estimate: 2016.
Office of National Statistics, 2017. Drug Misuse: Findings from the 2016/17 Crime Survey from England and Wales.
  • Olsson, A.C., Vermeulen, R., Schüz, J., Kromhout, H., Pesch, B., Peters, S., Behrens, T., Portengen, L., Mirabelli, D., Gustavsson, P. and Kendzia, B., 2017. Exposure–Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case–Control Studies. Epidemiology (Cambridge, Mass.), 28(2), p.288.
  • Ong, T., Sahota, O., Tan, W. and Marshall, L., 2014. A United Kingdom perspective on the relationship between body mass index (BMI) and bone health: a cross sectional analysis of data from the Nottingham Fracture Liaison Service. Bone, 59, pp.207-210.
  • Ornello, R., Ripa, P., Pistoia, F., Degan, D., Tiseo, C., Carolei, A. and Sacco, S., 2015. Migraine and body mass index categories: a systematic review and meta-analysis of observational studies. The Journal of Headache and Pain, 16(1), p.27.
  • Osborn, A.J., Mathias, J.L. and Fairweather-Schmidt, A.K., 2014. Depression following adult, non-penetrating traumatic brain injury: a meta-analysis examining methodological variables and sample characteristics. Neuroscience & Biobehavioral Reviews, 47, pp.1-15.
Parkin, D.M., 2011. 7. Cancers attributable to dietary factors in the UK in 2010. British Journal of Cancer, 105, pp.S31-S33.
  • Pedditizi, E., Peters, R. and Beckett, N., 2016. The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies. Age and Ageing, 45(1), pp.14-21.
  • Pesch, B., Kendzia, B., Gustavsson, P., Jöckel, K.H., Johnen, G., Pohlabeln, H., Olsson, A., Ahrens, W., Gross, I.M., Brüske, I. and Wichmann, H.E., 2012. Cigarette smoking and lung cancer—relative risk estimates for the major histological types from a pooled analysis of case–control studies. International Journal of Cancer, 131(5), pp.1210-1219.
  • Public Health England, 2011. Assessment of Dietary Sodium Levels Among Adults (aged 19-64) in England, 2011. Tables: Sodium Survey England 2011.
  • Public Health England, 2017. Radon in Homes in England 2016 Data Report. Rasouli, B., Andersson, T., Carlsson, P.O., Grill, V., Groop, L., Martinell, M., Storm, P., Tuomi, T. and Carlsson, S., 2016. Smoking and the risk of LADA: results from a Swedish population-based case-control study. Diabetes Care, p.dc152348.
  • Ratib, S., West, J., Crooks, C.J. and Fleming, K.M., 2014. Diagnosis of liver cirrhosis in England, a cohort study, 1998–2009: a comparison with cancer. The American Journal of Gastroenterology, 109(2), pp.190-198.
  • Schneider, C., Jick, S. S., Bothner, U., & Meier, C. R., 2010. Cancer risk in patients with chronic obstructive pulmonary disease. Pragmatic and Observational Research, 1, 15–23.
  • Sharma, M., Nazareth, I. and Petersen, I., 2016. Trends in incidence, prevalence and prescribing in type 2 diabetes mellitus between 2000 and 2013 in primary care: a retrospective cohort study. BMJ open, 6(1), p.e010210.
  • Simms, I., Talebi, A., Rhia, J., Horner, P., French, R.S., Sarah, R. and Macintosh, M., 2009. The English national chlamydia screening programme: variations in positivity in 2007/2008. Sexually Transmitted Diseases, 36(8), pp.522-527.
  • Slooter, A.J., Cruts, M., Kalmijn, S., Hofman, A., Breteler, M.M., Van Broeckhoven, C. and van Duijn, C.M., 1998. Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Archives of Neurology, 55(7), pp.964-968.
  • Smolina, K., Wright, F.L., Rayner, M. and Goldacre, M.J., 2012. Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: national-linked database study. The European Journal of Public Health, 22(6), pp.848-853.
  • Sonder, G.J., Van Rijckevorsel, G.G. and Van Den Hoek, A., 2009. Risk of hepatitis B for travelers: is vaccination for all travelers really necessary?. Journal of Travel Medicine, 16(1), pp.18-22.
  • Spitzer, R.L., Kroenke, K., Williams, J.B. and Löwe, B., 2006. A brief measure for assessing generalized anxiety disorder: the GAD-7. Archives of Internal Medicine, 166(10), pp.1092-1097.
  • Spitzer, R.L., Kroenke, K., Williams, J.B. and Patient Health Questionnaire Primary Care Study Group, 1999. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. JAMA, 282(18), pp.1737-1744.
  • Sport England, 2016. Active People Interactive.
  • Stang, P., Sternfeld, B. and Sidney, S., 1996. Migraine headache in a prepaid health plan: ascertainment, demographics, physiological, and behavioral factors. Headache: the journal of head and face pain, 36(2), pp.69-76.
  • Stewart, W.F., Bigal, M.E., Kolodner, K., Dowson, A., Liberman, J.N. and Lipton, R.B., 2006. Familial risk of migraine Variation by proband age at onset and headache severity. Neurology, 66(3), pp.344-348.
  • Svanes, C., Sunyer, J., Plana, E., Dharmage, S., Heinrich, J., Jarvis, D., De Marco, R., Norbäck, D., Raherison, C., Villani, S. and Wjst, M., 2010. Early life origins of chronic obstructive pulmonary disease. Thorax, 65(1), pp.14-20.
  • Tagalakis, V., Tamim, H., Blostein, M., Collet, J.P., Hanley, J.A. and Kahn, S.R., 2007. Use of warfarin and risk of urogenital cancer: a population-based, nested case-control study. The Lancet Oncology, 8(5), pp.395-402.
  • Tapper, E.B., Krajewski, K., Lai, M., Challies, T., Kane, R., Afdhal, N. and Lau, D., 2014. Simple non-invasive biomarkers of advanced fibrosis in the evaluation of non-alcoholic fatty liver disease. Gastroenterology Report, 2(4), pp.276-280.
  • The Health & Social Care Information Centre, 2013. Health Survey England: Adult Cigarette Smoking.
  • The Health & Social Care Information Centre, Social Care Statistics, 2016. Adult psychiatric morbidity survey 2014, Chapter 2: Common Mental Disorders- Data Tables.
  • Thögersen, A.M., Jansson, J.H., Boman, K., Nilsson, T.K., Weinehall, L., Huhtasaari, F. and Hallmans, G., 1998. High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infarction in both men and women. Circulation, 98(21), pp.2241-2247.
  • Toivanen, A.T., Heliövaara, M., Impivaara, O., Arokoski, J.P., Knekt, P., Lauren, H. and Kröger, H., 2009. Obesity, physically demanding work and traumatic knee injury are major risk factors for knee osteoarthritis—a population-based study with a follow-up of 22 years. Rheumatology, 49(2), pp.308-314.
  • Townsend, N., Wickramasinghe, K., Bhatnagar, P., Smolina, K., Nichols, M., Leal, J., Luengo-Fernandez, R. and Rayner, M., 2012. Coronary Heart Disease Statistics: A Compendium of Health Statistics, 2012 ed. British Hearth Foundation: London, UK.
Van Staa, T.P., Leufkens, H.G.M., Abenhaim, L., Begaud, B., Zhang, B. and Cooper, C., 2000. Use of oral corticosteroids in the United Kingdom. QJM, 93(2), pp.105-111.
van Zon, S.K., Snieder, H., Bültmann, U. and Reijneveld, S.A., 2017.
  • The interaction of socioeconomic position and type 2 diabetes mellitus family history: a cross-sectional analysis of the Lifelines Cohort and Biobank Study. BMJ open, 7(4), p.e015275.
  • Varghese, D., Saha, S., Scott, J.D., Chan, R.C.K., McGrath, J.J., n.d. The association between family history of mental disorder and delusional-like experiences: A general population study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156, 478–483. https://doi.org/10.1002/ajmg.b.31185
  • Veldhuijzen, I.K. and Smits, L.J., 2005. The importance of imported infections in maintaining hepatitis B in The Netherlands. Epidemiology & Infection, 133(1), pp.113-119.
  • Veličko, I., Ploner, A., Sparén, P., Marions, L., Herrmann, B. and Kühlmann-Berenzon, S., 2016. Sexual and testing behaviour associated with Chlamydia trachomatis infection: a cohort study in an STI clinic in Sweden. BMJ Open, 6(8), p.e011312.
  • Vestergaard, P., Rejnmark, L. and Mosekilde, L., 2005. Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk. Diabetologia, 48(7), pp.1292-1299.
  • Vestergaard, P., Rejnmark, L., Weeke, J., Hoeck, H.C., Nielsen, H.K., Rungby, J., Laurberg, P. and Mosekilde, L., 2002. Smoking as a risk factor for Graves' disease, toxic nodular goiter, and autoimmune hypothyroidism. Thyroid, 12(1), pp.69-75.
  • Vyse, A.J., Gay, N.J., Hesketh, L.M., Andrews, N.J., Marshall, B., Thomas, H.I.J., Morgan-Capner, P. and Miller, E., 2002. The burden of Helicobacter pylori infection in England and Wales. Epidemiology & Infection, 128(3), pp.411-417.
  • Wald, A., Koutsky, L., Ashley, R.L. and Corey, L., 1997. Genital herpes in a primary care clinic: demographic and sexual correlates of herpes simplex type 2 infections. Sexually Transmitted Diseases, 24(3), pp.149-155.
  • Weich, S., Blanchard, M., Prince, M., Burton, E., Erens, B.O.B. and Sproston, K., 2002. Mental health and the built environment: cross-sectional survey of individual and contextual risk factors for depression. The British Journal of Psychiatry, 180(5), pp.428-433.
  • Winsa, B., Adami, H.O., Bergstrom, R., Gamstedt, A., Dahlberg, P.A., Adamson, U., Jansson, R. and Karlsson, A., 1991. Stressful life events and Graves' disease. The Lancet, 338(8781), pp.1475-1479.
  • Wittchen, H.U., Zhao, S., Kessler, R.C. and Eaton, W.W., 1994. DSM-III-R generalized anxiety disorder in the National Comorbidity Survey. Archives of General Psychiatry, 51(5), pp.355-364.
  • Woestenberg, P.J., Tjhie, J.H., de Melker, H.E., van der Klis, F.R., van Bergen, J.E.M., van der Sande, M.A. and van Benthem, B.H., 2016. Herpes simplex virus type 1 and type 2 in the Netherlands: seroprevalence, risk factors and changes during a 12-year period. BMC Infectious Diseases, 16(1), p.364.
  • Wolters, F.J., van der Lee, S.J., Koudstaal, P.J., van Duijn, C.M., Hofman, A., Ikram, M.K., Vernooij, M.W. and Ikram, M.A., 2017. Parental family history of dementia in relation to subclinical brain disease and dementia risk. Neurology, 88(17), pp.1642-1649.
  • Woo, D., Sauerbeck, L.R., Kissela, B.M., Khoury, J.C., Szaflarski, J.P., Gebel, J., Shukla, R., Pancioli, A.M., Jauch, E.C., Menon, A.G. and Deka, R., 2002. Genetic and environmental risk factors for intracerebral hemorrhage. Stroke, 33(5), pp.1190-1196.
  • World Health Organization, 2017. Asbestos: elimination of asbestos-related diseases.
  • Wright, J., Johns, R., Watt, I., Melville, A. and Sheldon, T., 1997. Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: a systematic review of the research evidence. BMJ, 314(7084), p.851.
  • Wutzler, P., Doerr, H.W., Färber, I., Eichhorn, U., Helbig, B., Sauerbrei, A., Brandstädt, A. and Rabenau, H.F., 2000. Seroprevalence of herpes simplex virus type 1 and type 2 in selected German populations—relevance for the incidence of genital herpes. Journal of Medical Virology, 61(2), pp.201-207.
  • Yip, A.G., Brayne, C. and Matthews, F.E., 2006. Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case–control study. Age and Ageing, 35(2), pp.154-160.
  • Yusuf, S., Hawken, S., Ôunpuu, S., Bautista, L., Franzosi, M.G., Commerford, P., Lang, C.C., Rumboldt, Z., Onen, C.L., Lisheng, L. and Tanomsup, S., 2005. Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study. The Lancet, 366(9497), pp.1640-1649.
  • Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J. and Lisheng, L., 2004. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. The Lancet, 364(9438), pp.937-952.
  • Zivadinov, R., Willheim, K., Sepic‐Grahovac, D., Jurjevic, A., Bucuk, M., Brnabic‐Razmilic, O., Relja, G. and Zorzon, M., 2003. Migraine and tension‐type headache in Croatia: a population‐based survey of precipitating factors. Cephalalgia, 23(5), pp.336-343.